DAAM2
Disheveled-associated activator of morphogenesis 2 is a protein that in humans is encoded by DDAM2 gene. Key regulator of the Wnt signaling pathway, which is required for various processes during development, such as dorsal patterning, determination of left/right symmetry or myelination in the central nervous system. Acts downstream of Wnt ligands and upstream of beta-catenin (CTNNB1). Required for canonical Wnt signaling pathway during patterning in the dorsal spinal cord by promoting the aggregation of Disheveled (Dvl) complexes, thereby clustering and formation of Wnt receptor signalosomes and potentiating Wnt activity. During dorsal patterning of the spinal cord, inhibits oligodendrocytes differentiation via interaction with PIP5K1A.
DAAM2 Antibodies
DAAM2 for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA774794ESR2HU | DAAM2 Antibody | Human | ELISA, IHC |
| CSB-PA774794LA01HU | DAAM2 Antibody | Human | ELISA, IHC |
DAAM2 Proteins
DAAM2 Proteins for Mus musculus (Mouse)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP773901MO CSB-EP773901MO CSB-BP773901MO CSB-MP773901MO CSB-EP773901MO-B |
Recombinant Mouse Disheveled-associated activator of morphogenesis 2 (Daam2), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
DAAM2 Proteins for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP774794HU CSB-EP774794HU CSB-BP774794HU CSB-MP774794HU CSB-EP774794HU-B |
Recombinant Human Disheveled-associated activator of morphogenesis 2 (DAAM2), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
