CREB3
Cyclic AMP-responsive element-binding protein 3 is a protein in humans that is encoded by CREB3 gene. Endoplasmic reticulum (ER)-bound transcription factor that plays a role in the unfolded protein response (UPR). Involved in cell proliferation and migration, tumor suppression and inflammatory gene expression. Plays also a role in the human immunodeficiency virus type 1 (HIV-1) virus protein expression and in the herpes simplex virus-1 (HSV-1) latent infection and reactivation from latency. Isoform 2 represses the VP16-mediated transactivation of immediate early genes of the HSV-1 virus by sequestring host cell factor-1 HCFC1 in the ER membrane of sensory neurons, thereby preventing the initiation of the replicative cascade leading to latent infection. Isoform 3 functions as a negative transcriptional regulator in ligand-induced transcriptional activation of the glucocorticoid receptor NR3C1 by recruiting and activating histone deacetylases (HDAC1, HDAC2 and HDAC6).
CREB3 Antibodies
CREB3 for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA005948GA01HU | CREB3 Antibody | Human | ELISA,WB,IHC |
| CSB-PA005948ESR1HU | CREB3 Antibody | Human | ELISA, WB, IHC |
CREB3 Proteins
CREB3 Proteins for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP005948HU1 CSB-EP005948HU1 CSB-BP005948HU1 CSB-MP005948HU1 CSB-EP005948HU1-B |
Recombinant Human Cyclic AMP-responsive element-binding protein 3 (CREB3), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF005948HU | Recombinant Human Cyclic AMP-responsive element-binding protein 3 (CREB3) | in vitro E.coli expression system |
CREB3 Proteins for Mus musculus (Mouse)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP720262MO CSB-EP720262MO CSB-BP720262MO CSB-MP720262MO CSB-EP720262MO-B |
Recombinant Mouse Cyclic AMP-responsive element-binding protein 3 (Creb3), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CREB3 Proteins for Bos taurus (Bovine)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP823364BO CSB-EP823364BO CSB-BP823364BO CSB-MP823364BO CSB-EP823364BO-B |
Recombinant Bovine Cyclic AMP-responsive element-binding protein 3 (CREB3), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
