CD86
CD86，即分化簇86，別名B7-2、CD28配體2。它是一種主要表達在抗原呈遞細胞上的共刺激分子，屬于免疫球蛋白超家族成員。CD86由人體細胞自身的基因編碼，其作用機制主要是通過與T細胞表面的CD28或CTLA-4（細胞毒性T淋巴細胞相關蛋白4）相互作用，提供共刺激信號，從而促進T細胞的激活、增殖和分化。在M1型巨噬細胞（促炎性巨噬細胞）中，CD86的表達水平通常較高，可以與T細胞的CD28結合，促進T細胞的活化，加強免疫應答和炎癥反應 。在生物學意義上，CD86在免疫應答中扮演著重要角色。它參與了T細胞的激活過程，對維持免疫平衡和調節(jié)免疫反應的強度至關重要。此外，CD86的表達也與某些疾病的發(fā)生發(fā)展有關，例如在自身免疫疾病和慢性炎癥性疾病中，CD86的異常表達可能導致免疫反應的失調。因此，針對CD86的治療策略正在被研究，以期用于治療相關疾病 。
熱銷產品
CD86 Recombinant Monoclonal Antibody (CSB-RA004965A0HU)
驗證數(shù)據(jù)
Western Blot
Positive WB detected in Hela whole cell lysate
All lanes CD86 antibody at 0.55μg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 70 KDa
Observed band size: 70 KDa
CD86 Antibodies
CD86 for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA004965GA01HU | CD86 Antibody | Human, Rat | ELISA, WB, IHC, IF, FC |
| CSB-PA004965EA01HU | CD86 Antibody | Human | ELISA |
| CSB-RA004965A0HU | CD86 Recombinant Monoclonal Antibody | Human | ELISA, WB |
CD86 Proteins
CD86 Proteins for Mus musculus (Mouse)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP004959MO1 CSB-EP004959MO1 CSB-BP004959MO1 CSB-MP004959MO1 CSB-EP004959MO1-B |
Recombinant Mouse T-lymphocyte activation antigen CD80 (Cd80), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-YP004965MO1 CSB-EP004965MO1 CSB-BP004965MO1 CSB-MP004965MO1 CSB-EP004965MO1-B |
Recombinant Mouse T-lymphocyte activation antigen CD86 (Cd86), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF004959MO | Recombinant Mouse T-lymphocyte activation antigen CD80 (Cd80) | in vitro E.coli expression system |
| CSB-CF004965MO | Recombinant Mouse T-lymphocyte activation antigen CD86 (Cd86) | in vitro E.coli expression system |
CD86 Proteins for Oryctolagus cuniculus (Rabbit)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP004965RB1 CSB-EP004965RB1 CSB-BP004965RB1 CSB-MP004965RB1 CSB-EP004965RB1-B |
Recombinant Rabbit T-lymphocyte activation antigen CD86 (CD86), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF004965RB | Recombinant Rabbit T-lymphocyte activation antigen CD86 (CD86) | in vitro E.coli expression system |
CD86 Proteins for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP004965HU1 CSB-EP004965HU1 CSB-BP004965HU1 CSB-MP004965HU1 CSB-EP004965HU1-B |
Recombinant Human T-lymphocyte activation antigen CD86 (CD86), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF004965HU | Recombinant Human T-lymphocyte activation antigen CD86 (CD86) | in vitro E.coli expression system |
| CSB-AP005161HU | Recombinant Human T-lymphocyte activation antigen CD86 (CD86), partial (Active) | Mammalian cell |
CD86 ELISA Kit
CD86 ELISA Kit for Mus musculus (Mouse)
| 產品貨號 | 產品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-EL004959MO | Mouse T-lymphocyte activation antigen CD80(CD80) ELISA kit | serum, plasma, tissue homogenates | 3.9 pg/mL |
CD86 ELISA Kit for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-E08542h | Human soluble Cluster of differentiation 86,sCD86 ELISA Kit | serum, plasma, tissue homogenates | 0.078 ng/mL |
