CD24
CD24：火熱在研新藥EXO-CD24，“搭載”外泌體，抵抗COVID-19？
CD24是一種熱穩(wěn)定抗原，屬于糖基磷脂酰肌醇（GPI）錨定的細(xì)胞表面蛋白。CD24最初被認(rèn)為是B細(xì)胞的標(biāo)記物，在B細(xì)胞分化早期階段表達(dá)，同時(shí)對(duì)淋巴細(xì)胞成熟、神經(jīng)系統(tǒng)發(fā)育及生理狀態(tài)下的組織更新起到重要的作用。CD24主要表達(dá)于造血系統(tǒng)的細(xì)胞、神經(jīng)組織以及一些特定的上皮細(xì)胞，同時(shí)也見于大多實(shí)體腫瘤、炎癥組織以及自身免疫性疾病的某些細(xì)胞。眾多研究發(fā)現(xiàn)，CD24在生理與病理狀態(tài)下具有完全相反的作用——在生理狀態(tài)下，CD24可抑制組織生長(zhǎng)；但在病理狀態(tài)下，CD24卻促進(jìn)細(xì)胞增殖。這些生理特性使得CD24在自身免疫性疾病、炎癥、腫瘤等疾病的治療研究中受到關(guān)注。
CUSABIO-哺乳Nanodisc技術(shù)平臺(tái)成功開發(fā)CD24活性蛋白。
The Validated Data of CD24-Nanoparticle (Active)
Purity was greater than 95% as determined by SDS-PAGE. (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Immobilized human CD24 at 2 μg/ml can bind anti-CD24 recombinant Monoclonal Antibody (CSB-RA004902A0HU). The EC50 is 5.409-8.219 ng/ml.
CD24 Antibodies
CD24 for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA004902GA01HU | CD24 Antibody | Human | ELISA,WB |
| CSB-PA006361 | CD24 Antibody | Human,Mouse,Rat | WB, ELISA |
| CSB-PA254759 | CD24 Antibody | Human | ELISA,IHC |
| CSB-PA202955 | CD24 Antibody | Human | IHC,ELISA |
| CSB-PA10468A0Rb | CD24 Antibody | Human | ELISA, IF |
| CSB-PA10468B0Rb | CD24 Antibody, HRP conjugated | Human | ELISA |
| CSB-PA10468C0Rb | CD24 Antibody, FITC conjugated | Human | |
| CSB-PA10468D0Rb | CD24 Antibody, Biotin conjugated | Human | ELISA |
CD24 Proteins
CD24 Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-EP004902HU CSB-BP004902HU CSB-EP004902HU-B |
Recombinant Human Signal transducer CD24 (CD24) | E.coli Baculovirus In Vivo Biotinylation in E.coli |
| CSB-RP104644h | Recombinant Human Signal transducer CD24 (CD24) | E.coli |
| CSB-MP004902HU | Recombinant Human Signal transducer CD24 (CD24)-Nanoparticle (Active) | Mammalian cell |
CD24 Proteins for Mus musculus (Mouse)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP329506MO CSB-EP329506MO CSB-BP329506MO CSB-MP329506MO CSB-EP329506MO-B |
Recombinant Mouse Signal transducer CD24 (Cd24) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
