CBLB
CBLB，即Casitas B淋巴瘤原癌基因B，別名Cbl-b、Nbla00127、RNF56。它來源于人類基因組，具體由CBLB基因編碼。CBLB是一種RING型E3泛素連接酶，屬于Cbl家族成員，在調節T細胞功能方面發揮核心作用。其作用機制是通過促進特定底物的泛素化，進而調控這些底物的降解或功能，從而負向調節免疫功能。在生物學上，CBLB的活性抑制可以增強抗腫瘤免疫效應，因為它能夠減少腫瘤細胞通過高表達CBLB實現的免疫逃逸。因此，CBLB在癌癥免疫治療中具有重要的研究價值和應用前景。
熱銷產品
Recombinant Human E3 ubiquitin-protein ligase CBL-B (CBLB), partial
CSB-YP623789HU
來源：Yeast
CSB-EP623789HU
來源：E.coli
CSB-BP623789HU
來源：Baculovirus
CSB-MP623789HU
來源：Mammalian cell
CSB-EP623789HU-B
來源：In Vivo Biotinylation in E.coli
CBLB Antibodies
CBLB for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA004579GA01HU | CBLB Antibody | Human,Mouse,Rat | ELISA,WB,IHC,IP |
CBLB Proteins
CBLB Proteins for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP623789HU CSB-EP623789HU CSB-BP623789HU CSB-MP623789HU CSB-EP623789HU-B |
Recombinant Human E3 ubiquitin-protein ligase CBL-B (CBLB), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CBLB Proteins for Mus musculus (Mouse)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP667545MO CSB-EP667545MO CSB-BP667545MO CSB-MP667545MO CSB-EP667545MO-B |
Recombinant Mouse E3 ubiquitin-protein ligase CBL-B (Cblb), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CBLB Proteins for Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP715671XBF CSB-EP715671XBF CSB-BP715671XBF CSB-MP715671XBF CSB-EP715671XBF-B |
Recombinant Xenopus tropicalis E3 ubiquitin-protein ligase CBL-B (cblb), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CBLB Proteins for Rattus norvegicus (Rat)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP814329RA CSB-EP814329RA CSB-BP814329RA CSB-MP814329RA CSB-EP814329RA-B |
Recombinant Rat E3 ubiquitin-protein ligase CBL-B (Cblb), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
