C5AR1
C5AR1，即補(bǔ)體成分5a受體1，別名CD88。它是一種G蛋白偶聯(lián)受體，主要在粒細(xì)胞、單核細(xì)胞、樹突狀細(xì)胞和髓源性抑制細(xì)胞（MDSC）以及腫瘤細(xì)胞上表達(dá)。C5AR1的作用機(jī)制是通過與補(bǔ)體激活片段C5a結(jié)合，激活下游的G蛋白和β-抑制素信號通路，從而在先天性免疫反應(yīng)中發(fā)揮關(guān)鍵作用。C5a-C5aR1軸的功能障礙與許多炎癥和免疫介導(dǎo)的疾病有關(guān)，包括腫瘤的發(fā)生發(fā)展。C5AR1不僅參與免疫細(xì)胞的激活和趨化，還與腫瘤微環(huán)境的免疫調(diào)節(jié)有關(guān)，其表達(dá)水平在多種腫瘤中升高，可預(yù)測疾病進(jìn)展和預(yù)后的生物標(biāo)志物，以及潛在的治療靶點(diǎn)。
熱銷產(chǎn)品
Recombinant Human C5a anaphylatoxin chemotactic receptor 1 (C5AR1)-VLPs (Active) (CSB-MP003996HU)
驗(yàn)證數(shù)據(jù)
CSB-MP003996HU is detected by Mouse anti-6*His monoclonal antibody.
Activity
Measured by its binding ability in a functional ELISA. Immobilized human C5AR1 at 10 μg/ml can bind Anti-C5AR1 recombinant antibody (CSB-RA003996A0HU), the EC50 is 1.239-3.760 ng/mL.
The presence of VLP-like structures was confirmed by TEM
C5AR1 Recombinant Monoclonal Antibody (CSB-RA003996A0HU)
驗(yàn)證數(shù)據(jù)
The Binding Activity of Human C5AR1-VLPs with Anti-C5AR1 recombinant Antibody
Activity: Measured by its binding ability in a functional ELISA. Immobilized Human C5AR1 (CSB-MP003996HU) at 10 μg/mL can bind Anti-C5AR1 recombinant antibody, the EC50 is 1.239-3.760 ng/mL.
C5AR1 Antibodies
C5AR1 for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA003996GA01HU | C5AR1 Antibody | Human,Mouse,Rat | ELISA,WB,IF |
| CSB-PA001479 | C5AR1 Antibody | Human | WB, IHC, IF, ELISA |
| CSB-PA060025 | Phospho-C5AR1 (S338) Antibody | Human | IHC, ELISA |
| CSB-PA003996LA01HU | C5AR1 Antibody | Human | ELISA, WB, IHC |
| CSB-RA003996A0HU | C5AR1 Recombinant Monoclonal Antibody | Human | ELISA |
C5AR1 Proteins
C5AR1 Proteins for Macaca mulatta (Rhesus macaque)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP003996MOW1 CSB-EP003996MOW1 CSB-BP003996MOW1 CSB-MP003996MOW1 CSB-EP003996MOW1-B |
Recombinant Macaca mulatta (Rhesus macaque) C5a anaphylatoxin chemotactic receptor (C5AR1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF003996MOW | Recombinant Macaca mulatta (Rhesus macaque) C5a anaphylatoxin chemotactic receptor (C5AR1) | in vitro E.coli expression system |
C5AR1 Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP003996HU1 CSB-BP003996HU1 CSB-MP003996HU1 |
Recombinant Human C5a anaphylatoxin chemotactic receptor (C5AR1), partial | Yeast Baculovirus Mammalian cell |
| CSB-CF003996HUd7 | Recombinant Human C5a anaphylatoxin chemotactic receptor 1 (C5AR1) | in vitro E.coli expression system |
| CSB-MP003996HU | Recombinant Human C5a anaphylatoxin chemotactic receptor 1 (C5AR1)-VLPs (Active) | Mammalian cell |
| CSB-EP003996HU1 | Recombinant Human C5a anaphylatoxin chemotactic receptor (C5AR1), partial | E.coli |
| CSB-EP003996HU1-B | Recombinant Human C5a anaphylatoxin chemotactic receptor (C5AR1), partial,Biotinylated | E.coli |
C5AR1 Proteins for Canis familiaris (Dog) (Canis lupus familiaris)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP003996DO1 CSB-EP003996DO1 CSB-BP003996DO1 CSB-MP003996DO1 CSB-EP003996DO1-B |
Recombinant Dog C5a anaphylatoxin chemotactic receptor 1 (C5AR1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF003996DO | Recombinant Dog C5a anaphylatoxin chemotactic receptor 1 (C5AR1) | in vitro E.coli expression system |
C5AR1 Proteins for Mus musculus (Mouse)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP003996MO1 CSB-BP003996MO1 CSB-MP003996MO1 |
Recombinant Mouse C5a anaphylatoxin chemotactic receptor (C5ar1), partial | Yeast Baculovirus Mammalian cell |
| CSB-CF003996MO | Recombinant Mouse C5a anaphylatoxin chemotactic receptor (C5ar1) | in vitro E.coli expression system |
C5AR1 Proteins for Cavia porcellus (Guinea pig)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP003996GU1 CSB-EP003996GU1 CSB-BP003996GU1 CSB-MP003996GU1 CSB-EP003996GU1-B |
Recombinant Guinea pig C5a anaphylatoxin chemotactic receptor 1 (C5AR1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF003996GU | Recombinant Guinea pig C5a anaphylatoxin chemotactic receptor 1 (C5AR1) | in vitro E.coli expression system |
C5AR1 Proteins for Pongo pygmaeus (Bornean orangutan)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP003996EXP1 CSB-EP003996EXP1 CSB-BP003996EXP1 CSB-MP003996EXP1 CSB-EP003996EXP1-B |
Recombinant Pongo pygmaeus C5a anaphylatoxin chemotactic receptor (C5AR1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF003996EXP | Recombinant Pongo pygmaeus C5a anaphylatoxin chemotactic receptor (C5AR1) | in vitro E.coli expression system |
C5AR1 Proteins for Gorilla gorilla gorilla (Lowland gorilla)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP003996GGZ1 CSB-EP003996GGZ1 CSB-BP003996GGZ1 CSB-MP003996GGZ1 CSB-EP003996GGZ1-B |
Recombinant Gorilla gorilla gorilla C5a anaphylatoxin chemotactic receptor (C5AR1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF003996GGZ | Recombinant Gorilla gorilla gorilla C5a anaphylatoxin chemotactic receptor (C5AR1) | in vitro E.coli expression system |
C5AR1 Proteins for Pan troglodytes (Chimpanzee)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP003996EQV1 CSB-EP003996EQV1 CSB-BP003996EQV1 CSB-MP003996EQV1 CSB-EP003996EQV1-B |
Recombinant Pan troglodytes C5a anaphylatoxin chemotactic receptor (C5AR1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF003996EQV | Recombinant Pan troglodytes C5a anaphylatoxin chemotactic receptor (C5AR1) | in vitro E.coli expression system |
C5AR1 Proteins for Rattus norvegicus (Rat)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP003996RA1 CSB-EP003996RA1 CSB-BP003996RA1 CSB-MP003996RA1 CSB-EP003996RA1-B |
Recombinant Rat C5a anaphylatoxin chemotactic receptor (C5ar1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF003996RA | Recombinant Rat C5a anaphylatoxin chemotactic receptor (C5ar1) | in vitro E.coli expression system |
C5AR1 Proteins for Danio rerio (Zebrafish) (Brachydanio rerio)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP003996DIL1 CSB-EP003996DIL1 CSB-BP003996DIL1 CSB-MP003996DIL1 CSB-EP003996DIL1-B |
Recombinant Danio rerio C5a anaphylatoxin chemotactic receptor (c5ar1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF003996DIL | Recombinant Danio rerio C5a anaphylatoxin chemotactic receptor (c5ar1) | in vitro E.coli expression system |
C5AR1 Proteins for Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP747619OEI1 CSB-EP747619OEI1 CSB-BP747619OEI1 CSB-MP747619OEI1 CSB-EP747619OEI1-B |
Recombinant Oncorhynchus mykiss C5a anaphylatoxin chemotactic receptor (c5ar1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF747619OEI | Recombinant Oncorhynchus mykiss C5a anaphylatoxin chemotactic receptor (c5ar1) | in vitro E.coli expression system |
C5AR1 Proteins for Oryctolagus cuniculus (Rabbit)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP874687RB1 CSB-EP874687RB1 CSB-BP874687RB1 CSB-MP874687RB1 CSB-EP874687RB1-B |
Recombinant Rabbit C5a anaphylatoxin chemotactic receptor (C5AR1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF874687RB | Recombinant Rabbit C5a anaphylatoxin chemotactic receptor (C5AR1) | in vitro E.coli expression system |
