C3

C3，即補體成分3，別名C3、C3adesArg、C3bc。C3是人體血漿中的主要補體成分之一，由肝臟細胞產(chǎn)生，是補體系統(tǒng)中心的蛋白質(zhì)。C3的作用機制包括作為補體級聯(lián)反應(yīng)的中心環(huán)節(jié)，它可以被多種途徑激活，包括經(jīng)典途徑、替代途徑和凝集素途徑。C3的激活導(dǎo)致其裂解為C3a和C3b兩個片段，其中C3b是效應(yīng)片段，能夠結(jié)合到病原體表面，促進吞噬作用，而C3a則是一個強效的過敏毒素。C3是補體系統(tǒng)的關(guān)鍵組成部分，參與了機體的免疫防御機制。C3的激活可以促進病原體的清除，增強吞噬細胞對病原體的識別和吞噬，同時C3b片段還可以參與形成膜攻擊復(fù)合物（MAC），導(dǎo)致病原體細胞的溶解。此外，C3還參與調(diào)節(jié)炎癥反應(yīng)，影響細胞黏附和細胞間相互作用。C3的異常調(diào)節(jié)與多種疾病有關(guān)，包括自身免疫性疾病、腎臟疾病和某些感染性疾病，因此，C3是免疫學(xué)研究和相關(guān)疾病治療中的一個潛在靶點。

熱銷產(chǎn)品

Recombinant Human Complement C3 (C3), partial (CSB-EP355590HU)

驗證數(shù)據(jù)

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

Based on the SEQUEST from database of E.coli host and target protein, the LC-MS/MS Analysis result of CSB-RP105994h could indicate that this peptide derived from E.coli-expressed Homo sapiens (Human) C3.

C3 Recombinant Monoclonal Antibody (CSB-RA303909A0HU)

驗證數(shù)據(jù)

Western Blot
Positive WB detected in: THP-1 whole cell lysate, K562 whole cell lysate
All lanes: C3 antibody at 1:1000
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 188 kDa
Observed band size: 115 kDa

IHC image of CSB-RA303909A0HU diluted at 1:100 and staining in paraffin-embedded human liver tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4℃ overnight. The primary is detected by a Goat anti-rabbit IgG polymer labeled by HRP and visualized using 0.05% DAB.

Overlay histogram showing HepG2 cells stained with CSB-RA303909A0HU (red line) at 1:50. The cells were fixed with 70% Ethylalcohol (18h) and then incubated in 10% normal goat serum to block non-specific protein-protein interactions followedby the antibody (1μg/1*10⁶ cells) for 1 h at 4℃.The secondary antibody used was FITC-conjugated goat anti-rabbit IgG (H+L) at 1/200 dilution for 30min at 4℃. Control antibody (green line) was Rabbit IgG (1μg/1*10⁶ cells) used under the same conditions. Acquisition of >10,000 events was performed.

C3 Antibody

C3 Protein

C3 ELISA Kit

C3 Antibodies

C3 for Homo sapiens (Human)

產(chǎn)品貨號	產(chǎn)品名稱	種屬反應(yīng)性	應(yīng)用類型
CSB-PA10599D0Rb	C3 Antibody, Biotin conjugated	Human	ELISA
CSB-PA10599B0Rb	C3 Antibody, HRP conjugated	Human	ELISA
CSB-PA10599A0Rb	C3 Antibody	Human	ELISA, IHC, IF
CSB-PA10599C0Rb	C3 Antibody, FITC conjugated	Human
CSB-RA303909A0HU	C3 Recombinant Monoclonal Antibody	Human	ELISA, WB, IHC, FC
CSB-RA699863A0HU	C3 Recombinant Monoclonal Antibody	Human	ELISA, IHC

C3 for Mus musculus (Mouse)

產(chǎn)品貨號	產(chǎn)品名稱	種屬反應(yīng)性	應(yīng)用類型
CSB-PA365507LA01MO	C3 Antibody	Mouse, Human	ELISA, WB
CSB-PA365507LB01MO	C3 Antibody, HRP conjugated	Mouse	ELISA
CSB-PA365507LC01MO	C3 Antibody, FITC conjugated	Mouse
CSB-PA365507LD01MO	C3 Antibody, Biotin conjugated	Mouse	ELISA

C3 for Rattus norvegicus (Rat)

產(chǎn)品貨號	產(chǎn)品名稱	種屬反應(yīng)性	應(yīng)用類型
CSB-PA360475HA01RA	C3 Antibody	Rat	ELISA
CSB-PA360475HB01RA	C3 Antibody, HRP conjugated	Rat	ELISA
CSB-PA360475HC01RA	C3 Antibody, FITC conjugated	Rat

C3 Proteins

C3 Proteins for Oryctolagus cuniculus (Rabbit)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP003888RB CSB-EP003888RB CSB-BP003888RB CSB-MP003888RB CSB-EP003888RB-B	Recombinant Rabbit Complement C3 alpha chain (C3), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

C3 Proteins for Sus scrofa (Pig)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-BP003888PI CSB-MP003888PI CSB-EP003888PI-B	Recombinant Pig Complement C3a anaphylatoxin (C3), partial	Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

C3 Proteins for Eptatretus burgeri (Inshore hagfish)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP310251EFF CSB-EP310251EFF CSB-BP310251EFF CSB-MP310251EFF CSB-EP310251EFF-B	Recombinant Eptatretus burgeri Complement C3 (C3), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

C3 Proteins for Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP311048OEI CSB-EP311048OEI CSB-BP311048OEI CSB-MP311048OEI CSB-EP311048OEI-B	Recombinant Oncorhynchus mykiss Complement C3 (c3), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

C3 Proteins for Cavia porcellus (Guinea pig)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP319396GU CSB-EP319396GU CSB-BP319396GU CSB-MP319396GU CSB-EP319396GU-B	Recombinant Guinea pig Complement C3 (C3), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

C3 Proteins for Enterobacteria phage P22 (Bacteriophage P22)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP319647EDG CSB-EP319647EDG CSB-BP319647EDG CSB-MP319647EDG CSB-EP319647EDG-B	Recombinant Enterobacteria phage P22 Regulatory protein C3 (C3)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

C3 Proteins for Clostridium botulinum D phage (Clostridium botulinum D bacteriophage)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP323391CLR CSB-EP323391CLR CSB-BP323391CLR CSB-MP323391CLR CSB-EP323391CLR-B	Recombinant Clostridium botulinum D phage Mono-ADP-ribosyltransferase C3 (C3)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

C3 Proteins for Beet curly top virus (strain California/Logan) (BCTV)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP324435BFX CSB-EP324435BFX CSB-BP324435BFX CSB-MP324435BFX CSB-EP324435BFX-B	Recombinant Beet curly top virus Replication enhancer (C3, L3)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

C3 Proteins for Tomato yellow leaf curl virus (strain Israel) (TYLCV)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP326697TGU CSB-EP326697TGU CSB-BP326697TGU CSB-MP326697TGU CSB-EP326697TGU-B	Recombinant Tomato yellow leaf curl virus Replication enhancer protein (C3, L3)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

C3 Proteins for Xenopus laevis (African clawed frog)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP329415XBE CSB-EP329415XBE CSB-BP329415XBE CSB-MP329415XBE CSB-EP329415XBE-B	Recombinant Xenopus laevis Complement C3 (c3)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

C3 Proteins for Tomato leaf curl virus (strain Australia) (ToLCV)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP334110TGF CSB-EP334110TGF CSB-BP334110TGF CSB-MP334110TGF CSB-EP334110TGF-B	Recombinant Tomato leaf curl virus Replication enhancer protein (C3, L3)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

C3 Proteins for Tomato yellow leaf curl Sardinia virus (TYLCSV)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP338820TGT CSB-EP338820TGT CSB-BP338820TGT CSB-MP338820TGT CSB-EP338820TGT-B	Recombinant Tomato yellow leaf curl Sardinia virus Replication enhancer protein (C3, L3)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

C3 Proteins for Tomato yellow leaf curl Sardinia virus (isolate Spain-1) (TYLCSV)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP339986TGS CSB-EP339986TGS CSB-BP339986TGS CSB-MP339986TGS CSB-EP339986TGS-B	Recombinant Tomato yellow leaf curl Sardinia virus Replication enhancer protein (C3, L3)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

C3 Proteins for Homo sapiens (Human)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP355590HU CSB-EP355590HU CSB-BP355590HU CSB-MP355590HU CSB-EP355590HU-B	Recombinant Human Complement C3 (C3), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-EP355590HU	Recombinant Human Complement C3 (C3), partial	E.coli

C3 Proteins for Caiman crocodilus (Spectacled caiman) (Caiman sclerops)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP355757CAF CSB-EP355757CAF CSB-BP355757CAF CSB-MP355757CAF CSB-EP355757CAF-B	Recombinant Caiman crocodilus Ig heavy chain V region C3 (C3)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

C3 Proteins for Rattus norvegicus (Rat)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP360475RA	Recombinant Rat Complement C3 (C3), partial	Yeast
CSB-EP360475RA CSB-BP360475RA CSB-MP360475RA CSB-EP360475RA-B	Recombinant Rat Complement C3 (C3), partial	E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

C3 Proteins for Bos taurus (Bovine)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP647263BO CSB-BP647263BO CSB-MP647263BO CSB-EP647263BO-B	Recombinant Bovine Complement C3 (C3), partial	Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-EP647263BO	Recombinant Bovine Complement C3 (C3), partial	E.coli

C3 Proteins for Clostridium limosum

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP673832CEAI CSB-EP673832CEAI CSB-BP673832CEAI CSB-MP673832CEAI CSB-EP673832CEAI-B	Recombinant Mono-ADP-ribosyltransferase C3 (c3)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

C3 Proteins for Microplitis demolitor bracovirus (isolate Webb) (MdBV)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP702426MDAK CSB-EP702426MDAK CSB-BP702426MDAK CSB-MP702426MDAK CSB-EP702426MDAK-B	Recombinant Microplitis demolitor bracovirus Uncharacterized protein C3 (C3)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

C3 Proteins for Tomato yellow leaf curl Sardinia virus (isolate Spain-2) (TYLCSV)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP731478TBAX CSB-EP731478TBAX CSB-BP731478TBAX CSB-MP731478TBAX CSB-EP731478TBAX-B	Recombinant Tomato yellow leaf curl Sardinia virus Replication enhancer protein (C3, L3)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

C3 Proteins for Tomato pseudo-curly top virus (TPCTV)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP801533TDAC CSB-EP801533TDAC CSB-BP801533TDAC CSB-MP801533TDAC CSB-EP801533TDAC-B	Recombinant Tomato pseudo-curly top virus Replication enhancer protein (C3, L3)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

C3 Proteins for Tomato yellow leaf curl China virus (TYLCCNV)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP887626TGAQ CSB-EP887626TGAQ CSB-BP887626TGAQ CSB-MP887626TGAQ CSB-EP887626TGAQ-B	Recombinant Tomato yellow leaf curl China virus Replication enhancer protein (C3, L3)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

C3 Proteins for Mus musculus (Mouse)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP365507MO CSB-BP365507MO CSB-MP365507MO CSB-EP365507MO-B	Recombinant Mouse Complement C3 (C3), partial	Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-EP365507MO	Recombinant Mouse Complement C3 (C3), partial	E.coli