BSG
Basigin（BSG），又稱CD147，是一種高度糖基化的、分子量為50～60kD的跨膜糖蛋白，屬于免疫球蛋白超家族（IgSF）成員。人BASIGIN由269個氨基酸組成，可分為胞外區(qū)、跨膜區(qū)及胞內(nèi)區(qū)。BSG可通過刺激腫瘤細胞自身及其周圍的成纖維細胞，分泌多種基質(zhì)金屬蛋白酶(extracellular matrix metalloproteinase，MMP)，包括MMP-1、MMP-2、MMP-3、MMP-11以及MT1-MMP和MT2-MMP等，從而加快腫瘤周圍基質(zhì)的降解，促進了腫瘤的轉(zhuǎn)移。已證實BASIGIN在許多類型的人實體瘤，如肺癌、肝癌、宮頸癌、結(jié)腸癌、乳腺癌、卵巢癌、食管癌或胃癌中過度表達。既往研究表明，Basigin分子是腫瘤發(fā)展過程重要的功能性膜蛋白，參與多種與癌癥有關的現(xiàn)象。目前，Basigin已被作為一種新的腫瘤標志物和治療靶點。
Recombinant Human BSG 活性蛋白實驗驗證數(shù)據(jù)
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Measured by its binding ability in a functional ELISA. Immobilized CD147 at 2 μg/ml can bind Anti-CD147 recombinant Antibody, the EC50 is 21.95-33.12 ng/ml.
BSG Antibodies
BSG for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA11759A0Rb | BSG Antibody | Human | ELISA, WB, IHC |
| CSB-PA11759C0Rb | BSG Antibody, FITC conjugated | Human | |
| CSB-PA002831GA01HU | BSG Antibody | Human | ELISA,WB,IHC |
| CSB-PA11759B0Rb | BSG Antibody, HRP conjugated | Human | ELISA |
| CSB-PA11759D0Rb | BSG Antibody, Biotin conjugated | Human | ELISA |
| CSB-PA002331 | BSG Antibody | Human,Mouse,Rat | WB, IHC, ELISA |
| CSB-PA005853 | BSG Antibody | Human | WB, ELISA |
| CSB-PA993569 | BSG Antibody | Human | ELISA,IHC |
| CSB-PA570608 | BSG Antibody | Human | ELISA,WB,IHC |
| CSB-RA002831A0HU | CD147 Recombinant Monoclonal Antibody | Human | ELISA, WB, IHC, IF, FC |
BSG Proteins
BSG Proteins for Mus musculus (Mouse)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP002831MO1 CSB-EP002831MO1 CSB-BP002831MO1 CSB-MP002831MO1 CSB-EP002831MO1-B |
Recombinant Mouse Basigin (Bsg), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF002831MO | Recombinant Mouse Basigin (Bsg) | in vitro E.coli expression system |
BSG Proteins for Gallus gallus (Chicken)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP002831CH1 CSB-EP002831CH1 CSB-BP002831CH1 CSB-MP002831CH1 CSB-EP002831CH1-B |
Recombinant Chicken Basigin (BSG), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF002831CH | Recombinant Chicken Basigin (BSG) | in vitro E.coli expression system |
BSG Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP002831HU CSB-EP002831HU CSB-BP002831HU CSB-EP002831HU-B |
Recombinant Human Basigin (BSG), partial | Yeast E.coli Baculovirus In Vivo Biotinylation in E.coli |
| CSB-RP117574h | Recombinant Human Basigin (BSG), partial | E.coli |
| CSB-CF002831HU | Recombinant Human Basigin (BSG) | in vitro E.coli expression system |
| CSB-MP002831HU | Recombinant Human Basigin (BSG), partial | Mammalian cell |
| CSB-MP002831HUf3 | Recombinant Human Basigin (BSG), partial | Mammalian cell |
| CSB-MP002831HU1 | Recombinant Human Basigin (BSG), partial (Active) | Mammalian cell |
BSG Proteins for Rattus norvegicus (Rat)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP002831RA1 CSB-EP002831RA1 CSB-BP002831RA1 CSB-MP002831RA1 CSB-EP002831RA1-B |
Recombinant Rat Basigin (Bsg), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF002831RA | Recombinant Rat Basigin (Bsg) | in vitro E.coli expression system |
BSG Proteins for Oryctolagus cuniculus (Rabbit)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP631727RB CSB-EP631727RB CSB-BP631727RB CSB-MP631727RB CSB-EP631727RB-B |
Recombinant Rabbit Basigin (BSG), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
BSG Proteins for Bos taurus (Bovine)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP771275BO CSB-EP771275BO CSB-BP771275BO CSB-MP771275BO CSB-EP771275BO-B |
Recombinant Bovine Basigin (BSG) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
BSG Proteins for Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP857519DXU CSB-EP857519DXU CSB-BP857519DXU CSB-MP857519DXU CSB-EP857519DXU-B |
Recombinant Cricetulus griseus Basigin (BSG), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
BSG ELISA Kit
BSG ELISA Kit for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-E12994h | Human Cluster of differentiation 147,CD147 Elisa Kit | serum, plasma | 3.12 pg/mL |
