BSG

Basigin（BSG），又稱CD147，是一種高度糖基化的、分子量為50～60kD的跨膜糖蛋白，屬于免疫球蛋白超家族（IgSF）成員。人BASIGIN由269個氨基酸組成，可分為胞外區(qū)、跨膜區(qū)及胞內(nèi)區(qū)。BSG可通過刺激腫瘤細(xì)胞自身及其周圍的成纖維細(xì)胞，分泌多種基質(zhì)金屬蛋白酶(extracellular matrix metalloproteinase，MMP)，包括MMP-1、MMP-2、MMP-3、MMP-11以及MT1-MMP和MT2-MMP等，從而加快腫瘤周圍基質(zhì)的降解，促進(jìn)了腫瘤的轉(zhuǎn)移。已證實(shí)BASIGIN在許多類型的人實(shí)體瘤，如肺癌、肝癌、宮頸癌、結(jié)腸癌、乳腺癌、卵巢癌、食管癌或胃癌中過度表達(dá)。既往研究表明，Basigin分子是腫瘤發(fā)展過程重要的功能性膜蛋白，參與多種與癌癥有關(guān)的現(xiàn)象。目前，Basigin已被作為一種新的腫瘤標(biāo)志物和治療靶點(diǎn)。

Recombinant Human BSG 活性蛋白實(shí)驗(yàn)驗(yàn)證數(shù)據(jù)

High Purity Validated by SDS-PAGE

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

Excellent Bioactivity Validated by Functional ELISA

Measured by its binding ability in a functional ELISA. Immobilized CD147 at 2 μg/ml can bind Anti-CD147 recombinant Antibody, the EC₅₀ is 21.95-33.12 ng/ml.

BSG Antibody

BSG Protein

BSG ELISA Kit

BSG Antibodies

BSG for Homo sapiens (Human)

產(chǎn)品貨號	產(chǎn)品名稱	種屬反應(yīng)性	應(yīng)用類型
CSB-PA11759A0Rb	BSG Antibody	Human	ELISA, WB, IHC
CSB-PA11759C0Rb	BSG Antibody, FITC conjugated	Human
CSB-PA002831GA01HU	BSG Antibody	Human	ELISA,WB,IHC
CSB-PA11759B0Rb	BSG Antibody, HRP conjugated	Human	ELISA
CSB-PA11759D0Rb	BSG Antibody, Biotin conjugated	Human	ELISA
CSB-PA002331	BSG Antibody	Human,Mouse,Rat	WB, IHC, ELISA
CSB-PA005853	BSG Antibody	Human	WB, ELISA
CSB-PA993569	BSG Antibody	Human	ELISA,IHC
CSB-PA570608	BSG Antibody	Human	ELISA,WB,IHC
CSB-RA002831A0HU	CD147 Recombinant Monoclonal Antibody	Human	ELISA, WB, IHC, IF, FC

BSG Proteins

BSG Proteins for Mus musculus (Mouse)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP002831MO1 CSB-EP002831MO1 CSB-BP002831MO1 CSB-MP002831MO1 CSB-EP002831MO1-B	Recombinant Mouse Basigin (Bsg), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-CF002831MO	Recombinant Mouse Basigin (Bsg)	in vitro E.coli expression system

BSG Proteins for Gallus gallus (Chicken)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP002831CH1 CSB-EP002831CH1 CSB-BP002831CH1 CSB-MP002831CH1 CSB-EP002831CH1-B	Recombinant Chicken Basigin (BSG), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-CF002831CH	Recombinant Chicken Basigin (BSG)	in vitro E.coli expression system

BSG Proteins for Homo sapiens (Human)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP002831HU CSB-EP002831HU CSB-BP002831HU CSB-EP002831HU-B	Recombinant Human Basigin (BSG), partial	Yeast E.coli Baculovirus In Vivo Biotinylation in E.coli
CSB-EP002831HU2	Recombinant Human Basigin (BSG), partial	E.coli
CSB-CF002831HU	Recombinant Human Basigin (BSG)	in vitro E.coli expression system
CSB-MP002831HU	Recombinant Human Basigin (BSG), partial	Mammalian cell
CSB-MP002831HUf3	Recombinant Human Basigin (BSG), partial	Mammalian cell
CSB-MP002831HU1	Recombinant Human Basigin (BSG), partial (Active)	Mammalian cell

BSG Proteins for Rattus norvegicus (Rat)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP002831RA1 CSB-EP002831RA1 CSB-BP002831RA1 CSB-MP002831RA1 CSB-EP002831RA1-B	Recombinant Rat Basigin (Bsg), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-CF002831RA	Recombinant Rat Basigin (Bsg)	in vitro E.coli expression system

BSG Proteins for Oryctolagus cuniculus (Rabbit)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP631727RB CSB-EP631727RB CSB-BP631727RB CSB-MP631727RB CSB-EP631727RB-B	Recombinant Rabbit Basigin (BSG), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

BSG Proteins for Bos taurus (Bovine)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP771275BO CSB-EP771275BO CSB-BP771275BO CSB-MP771275BO CSB-EP771275BO-B	Recombinant Bovine Basigin (BSG)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

BSG Proteins for Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP857519DXU CSB-EP857519DXU CSB-BP857519DXU CSB-MP857519DXU CSB-EP857519DXU-B	Recombinant Cricetulus griseus Basigin (BSG), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli