BET1
BET1，即Bet1高爾基體囊泡膜轉(zhuǎn)運(yùn)蛋白，別名HBET1。BET1是一種在人體中編碼的蛋白質(zhì)，屬于高爾基體相關(guān)膜蛋白，參與從內(nèi)質(zhì)網(wǎng)（ER）到高爾基復(fù)合體的囊泡運(yùn)輸過程。BET1蛋白作為可溶性N-乙基馬來酰亞胺敏感因子附著蛋白受體（SNARE）發(fā)揮作用，可能涉及ER衍生囊泡與順式高爾基體膜的對接，對蛋白質(zhì)的正確折疊、修飾和運(yùn)輸至關(guān)重要。該基因具有多個(gè)轉(zhuǎn)錄本變體，由可變剪接產(chǎn)生。BET1在生物學(xué)上的意義主要體現(xiàn)在其對細(xì)胞內(nèi)蛋白質(zhì)運(yùn)輸和代謝過程的調(diào)控作用。它在多種組織中都有表達(dá)，尤其在胎盤、腎上腺等組織中表達(dá)量較高。BET1的功能異常與某些疾病相關(guān)，例如新生兒期發(fā)病的II型瓜氨酸血癥（Citrullinemia, Type Ii, Neonatal-Onset）和由于檸檬酸缺乏引起的新生兒肝內(nèi)膽汁淤積癥（NICCD, Neonatal Intrahepatic Cholestasis Due To Citrin Deficiency）。BET1的活性和調(diào)控機(jī)制對于維持細(xì)胞內(nèi)環(huán)境的穩(wěn)定和細(xì)胞器間的通訊至關(guān)重要。
熱銷產(chǎn)品
BET1 Antibody (CSB-PA002670LA01HU)
驗(yàn)證數(shù)據(jù)
Western Blot
Positive WB detected in: K562 whole cell lysate, Rat brain tissue
All lanes: BET1 antibody at 3.4µg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 14, 10 kDa
Observed band size: 14 kDa
BET1 Antibodies
BET1 for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA002670LA01HU | BET1 Antibody | Human, Rat | ELISA, WB |
| CSB-PA002670LC01HU | BET1 Antibody, FITC conjugated | Human |
BET1 Proteins
BET1 Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP002670HU1 CSB-EP002670HU1 CSB-BP002670HU1 CSB-MP002670HU1 CSB-EP002670HU1-B |
Recombinant Human BET1 homolog (BET1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF002670HU | Recombinant Human BET1 homolog (BET1) | in vitro E.coli expression system |
