BAP1
Deubiquitinating enzyme that plays a key role in chromatin by mediating deubiquitination of histone H2A and HCFC1. Catalytic component of the PR-DUB complex, a complex that specifically mediates deubiquitination of histone H2A monoubiquitinated at 'Lys-119' (H2AK119ub1). Does not deubiquitinate monoubiquitinated histone H2B. Acts as a regulator of cell growth by mediating deubiquitination of HCFC1 N-terminal and C-terminal chains, with some specificity toward 'Lys-48'-linked polyubiquitin chains compared to 'Lys-63'-linked polyubiquitin chains. Deubiquitination of HCFC1 does not lead to increase stability of HCFC1. Interferes with the BRCA1 and BARD1 heterodimer activity by inhibiting their ability to mediate ubiquitination and autoubiquitination. It however does not mediate deubiquitination of BRCA1 and BARD1. Able to mediate autodeubiquitination via intramolecular interactions to couteract monoubiquitination at the nuclear localization signal (NLS), thereby protecting it from cytoplasmic sequestration. Acts as a tumor suppressor.
BAP1 Antibodies
BAP1 for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA002556GA01HU | BAP1 Antibody | Human | ELISA,WB |
| CSB-PA849763ESR2HU | BAP1 Antibody | Human | ELISA, WB |
| CSB-PA985124 | BAP1 Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
BAP1 Proteins
BAP1 Proteins for Bos taurus (Bovine)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP002556BO CSB-EP002556BO CSB-BP002556BO CSB-MP002556BO CSB-EP002556BO-B |
Recombinant Bovine Ubiquitin carboxyl-terminal hydrolase BAP1 (BAP1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
BAP1 Proteins for Rattus norvegicus (Rat)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP002556RA CSB-EP002556RA CSB-BP002556RA CSB-MP002556RA CSB-EP002556RA-B |
Recombinant Rat Ubiquitin carboxyl-terminal hydrolase BAP1 (Bap1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
BAP1 Proteins for Danio rerio (Zebrafish) (Brachydanio rerio)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP002556DIL CSB-EP002556DIL CSB-BP002556DIL CSB-MP002556DIL CSB-EP002556DIL-B |
Recombinant Danio rerio Ubiquitin carboxyl-terminal hydrolase BAP1 (bap1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
BAP1 Proteins for Branchiostoma floridae (Florida lancelet) (Amphioxus)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP002556BVY CSB-EP002556BVY CSB-BP002556BVY CSB-MP002556BVY CSB-EP002556BVY-B |
Recombinant Branchiostoma floridae Ubiquitin carboxyl-terminal hydrolase BAP1 (BAP1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
BAP1 Proteins for Gallus gallus (Chicken)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP682744CH CSB-EP682744CH CSB-BP682744CH CSB-MP682744CH CSB-EP682744CH-B |
Recombinant Chicken Ubiquitin carboxyl-terminal hydrolase BAP1 (BAP1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
BAP1 Proteins for Xenopus laevis (African clawed frog)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP690442XBE CSB-EP690442XBE CSB-BP690442XBE CSB-MP690442XBE CSB-EP690442XBE-B |
Recombinant Xenopus laevis Ubiquitin carboxyl-terminal hydrolase BAP1 (bap1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
BAP1 Proteins for Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP721087XBF CSB-EP721087XBF CSB-BP721087XBF CSB-MP721087XBF CSB-EP721087XBF-B |
Recombinant Xenopus tropicalis Ubiquitin carboxyl-terminal hydrolase BAP1 (bap1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
BAP1 Proteins for Arabidopsis thaliana (Mouse-ear cress)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP846376DOA CSB-EP846376DOA CSB-BP846376DOA CSB-MP846376DOA CSB-EP846376DOA-B |
Recombinant Arabidopsis thaliana BON1-associated protein 1 (BAP1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
BAP1 Proteins for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP849763HU CSB-EP849763HU CSB-BP849763HU CSB-MP849763HU CSB-EP849763HU-B |
Recombinant Human Ubiquitin carboxyl-terminal hydrolase BAP1 (BAP1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
BAP1 Proteins for Mus musculus (Mouse)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP858174MO CSB-EP858174MO CSB-BP858174MO CSB-MP858174MO CSB-EP858174MO-B |
Recombinant Mouse Ubiquitin carboxyl-terminal hydrolase BAP1 (Bap1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
