ERCC2
General transcription and DNA repair factor IIH helicase subunit XPD is a protein in humans that is encoded by ERCC2 gene. ATP-dependent 5'-3' DNA helicase, component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II. In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. The ATP-dependent helicase activity of XPD/ERCC2 is required for DNA opening. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape.
ERCC2 Antibodies
ERCC2 for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA007770GA01HU | ERCC2 Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
| CSB-PA007770ESR1HU | ERCC2 Antibody | Human | ELISA, IHC |
| CSB-PA007770ESR2HU | ERCC2 Antibody | Human | ELISA, WB, IHC |
ERCC2 Proteins
ERCC2 Proteins for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP007770HU CSB-EP007770HU CSB-BP007770HU CSB-MP007770HU CSB-EP007770HU-B |
Recombinant Human TFIIH basal transcription factor complex helicase XPD subunit (ERCC2) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ERCC2 Proteins for Bos taurus (Bovine)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP007770BO CSB-EP007770BO CSB-BP007770BO CSB-MP007770BO CSB-EP007770BO-B |
Recombinant Bovine TFIIH basal transcription factor complex helicase XPD subunit (ERCC2), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ERCC2 Proteins for Mus musculus (Mouse)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP007770MO CSB-EP007770MO CSB-BP007770MO CSB-MP007770MO CSB-EP007770MO-B |
Recombinant Mouse TFIIH basal transcription factor complex helicase XPD subunit (Ercc2) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ERCC2 Proteins for Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP720137DXU CSB-EP720137DXU CSB-BP720137DXU CSB-MP720137DXU CSB-EP720137DXU-B |
Recombinant Cricetulus griseus TFIIH basal transcription factor complex helicase XPD subunit (ERCC2), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
