Recombinant Regulatory protein BlaR1 (blaR1)

in vitro E.coli expression system

中文名稱：

Recombinant Regulatory protein BlaR1(blaR1)
貨號：

CSB-CF319385BQT
說明書：

MSDS Datasheet
規(guī)格：
來源：

in vitro E.coli expression system
其他：

產(chǎn)品詳情
產(chǎn)品評價(jià)
相關(guān)產(chǎn)品
靶點(diǎn)詳情

產(chǎn)品詳情

基因名：

blaR1
Uniprot No.：

P12287
別名：

blaR1; penR1; Regulatory protein BlaR1
種屬：

Bacillus licheniformis
蛋白長度：

full length protein
表達(dá)區(qū)域：

1-601
氨基酸序列

MSSSFFIPFLVSQILLSLFFSIIILIKKLLRTQITVGTHYYISVISLLALIAPFIPFHFL KSHHFDWILNLGGAQSALSQTHSTDKTTEAIGQHVNWVQDFSLSIEQSSSKMIDSAFFAV WILGVAVMLLATLYSNLKIGKIKKNLQIVNNKELLSLFHTCKEEIRFHQKVILSRSPLIK SPITFGVIRPYIILPKDISMFSADEMKCVLLHELYHCKRKDMLINYFLCLLKIVYWFNPL VWYLSKEAKTEMEISCDFAVLKTLDKKLHLKYGEVILKFTSIKQRTSSLLAASEFSSSYK HIKRRIVTVVNFQTASPLLKAKSALVFTLVLGAILAGTPSVSILAMQKETRFLPGTNVEY EDYSTFFDKFSASGGFVLFNSNRKKYTIYNRKESTSRFAPASTYKVFSALLALESGIITK NDSHMTWDGTQYPYKEWNQDQDLFSAMSSSTTWYFQKLDRQIGEDHLRHYLKSIHYGNED FSVPADYWLDGSLQISPLEQVNILKKFYDNEFDFKQSNIETVKDSIRLEESNGRVLSGKT GTSVINGELHAGWFIGYVETADNTFFFAVHIQGEKRAAGSSAAEIALSILDKKGIYPSVS R
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
蛋白標(biāo)簽：

N-terminal 10xHis-tagged
產(chǎn)品提供形式：

Liquid or Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
緩沖液：

Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質(zhì)期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項(xiàng)：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet & COA：

Please contact us to get it.

產(chǎn)品評價(jià)

靶點(diǎn)詳情

功能：

Integral membrane protein involved in sensing of the presence of beta-lactam antibiotics and transduction of the information to the cytoplasm. Mechanistically, activation of the signal transducer involves acylation of a serine in the C-terminal sensor domain upon binding of the beta-lactam antibiotic. In turn, a conformational change occurs and the signal is transmitted from the cell surface to the cytoplasm. There, the zinc protease domain is activated and initiates autoproteolysis as well as cleavage of the transcriptional repressor BlaI leading to derepression of antibiotic resistance genes.
亞細(xì)胞定位：

Cell membrane; Multi-pass membrane protein.
蛋白家族：

Peptidase M56 family