Recombinant Rat Leukotriene B4 receptor 1 (Ltb4r)

in vitro E.coli expression system

中文名稱：

大鼠Ltb4r重組蛋白
貨號：

CSB-CF886424RA
說明書：

MSDS Datasheet
規格：
來源：

in vitro E.coli expression system
其他：

產品詳情
產品評價
相關產品
靶點詳情

產品詳情

基因名：

Ltb4r
Uniprot No.：

Q9R0Q2
別名：

Ltb4r; Blt; Leukotriene B4 receptor 1; LTB4-R 1; LTB4-R1
種屬：

Rattus norvegicus (Rat)
蛋白長度：

full length protein
表達區域：

1-351
氨基酸序列

MAANTTSTAATSSPGGMSLSLLPIVLLSVALVVGLPGNSFVVWSILKRMQKRSVTALLVL NLALADLAVLLTAPFFLHFLARGTWSFEVTGCRLCHYVCGVSMYASVLLITIMSLDRSLA VARPFVSQKVRTKAFARWVLAGIWVVSFLLAIPVLVYRTVTPKNKTLICDSRYPSDGHKV FHLLFEAITGFLLPFLAVVASYSDIGRRLQARRFRRSRRTGRLVVLIILAFAAFWLPYHL VNLVEAGRTLAGWDKNSPAGQRLKLARYVLIALAFLSSSVNPVLYACAGGGLLRSAGVGF VVKLLEGTGSEVSSTRRGGTLVQTPKATPTCPEPGPTDSFMTSSTPPESSK
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
蛋白標簽：

N-terminal 10xHis-tagged
產品提供形式：

Liquid or Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
緩沖液：

Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet & COA：

Please contact us to get it.

產品評價

靶點詳情

功能：

Receptor for leukotriene B4, a potent chemoattractant involved in inflammation and immune response.
基因功能參考文獻：
1. Study verified that both BLT1 mRNA and BLT1 protein expressions were markedly increased after subarachnoid hemorrhage and elevated BLT1 expressions were mainly found in neurons, microglia and endothelial cells rather than astrocytes. We also demonstrated that there a significant positive correlation between BLT1 and nuclear p65 protein expressions in the same specific time course. PMID: 27725151
2. BLT1 and BLT2 were involved in synovial cell proliferation. PMID: 21189570
3. LTB4 down-regulates airway contraction and inflammation through activation of the hypothalamic-pituitary-adrenal axis via its BLT1 receptor. PMID: 20403205
4. The time-dependent expression of Ltb4r in experimental arthritis was studied. PMID: 17481560
5. FcgammaRI ligation leads to a complex with BLT1 in lipid rafts that enhances rat lung macrophage antimicrobial functions. PMID: 19657115
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亞細胞定位：

Cell membrane; Multi-pass membrane protein.
蛋白家族：

G-protein coupled receptor 1 family
組織特異性：

Exclusively expressed in polymorphonuclear leukocytes.
數據庫鏈接：

KEGG: rno:59264

STRING: 10116.ENSRNOP00000027647

UniGene: Rn.41003