Recombinant Rabbit Integrin beta-8 (ITGB8)

in vitro E.coli expression system

中文名稱：

小圓錐花果ITGB8重組蛋白
貨號：

CSB-CF011892RB
規格：
來源：

in vitro E.coli expression system
其他：

產品詳情
產品評價
相關產品
靶點詳情

產品詳情

基因名：

ITGB8
Uniprot No.：

P26013
別名：

ITGB8Integrin beta-8
種屬：

Oryctolagus cuniculus (Rabbit)
蛋白長度：

Full Length of Mature Protein
表達區域：

43-768
氨基酸序列

ENSRCASSHAVSCSECLALGPDCGWCVHEDFISGGPRSERCDIVSNLISKGCPVDSIEYPSVHVTIPSENEVNTQVTPGEVSIQLRPGAAANFMLKIHPLKKYPVDLYYLVDVSASMHNNIEKLNSVGNDLSRKMAFFSRDFRLGFGSYVDKTVSPYISIHPERIHNQCSDYNLDCMPPHGYIHVLSLTENITEFERAVHRQKISGNIDTPEGGFDAMLQAAVCESHIGWRKEAKRLLLVMTDQTSHLALDSKLAGIVVPNDGNCHLRNNVYVKSTTMEHPSLGQLSEKLIDNNINVIFAVQGKQFHWYKDLLPLLPGTIAGEIESKAANLNNLVVEAYQKLISEVKVQVESKVPGVYFNVTAICPDGARKLGMEGCSNVTSSDEVLFNVTVTMEKCSVTGGKNYAIIKPIGFNETSKIHIHQNCGCECEASRGGAAKCAEEAPLDSTCPQCQESQCHQEEAQSPSQGCKAHEDQPVCSGRGVCVCGKCLCHKMKLGKVYGKYCEKDDFSCPYHHGSLCAGHGECEAGRCQCFSGWEGDRCQCPSAAAQHCVNSKGQVCSGRGTCVCGRCECSDPRSIGRFCEHCPTCPTACSENWNCVQCLHPHNLSQAILDQCRTSCASMEQPYVEQASECFSSPSYLRIFFIIFIVTFLIGLLKILIIRQVILQWNSSKIKSSSDYRVSASKKDKLILQSVCTRAVTYRREKPEEIKLDISKLNAHETFRCNF
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
蛋白標簽：

10xHis-SUMO-tag
產品提供形式：

Liquid or Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
緩沖液：

Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet & COA：

Please contact us to get it.

產品評價

靶點詳情

功能：

Integrin alpha-V:beta-8 (ITGAV:ITGB8) is a receptor for fibronectin. It recognizes the sequence R-G-D in its ligands. Integrin alpha-V:beta-6 (ITGAV:ITGB6) mediates R-G-D-dependent release of transforming growth factor beta-1 (TGF-beta-1) from regulatory Latency-associated peptide (LAP), thereby playing a key role in TGF-beta-1 activation on the surface of activated regulatory T-cells (Tregs). Required during vasculogenesis.
亞細胞定位：

Cell membrane; Single-pass type I membrane protein.
蛋白家族：

Integrin beta chain family
組織特異性：

Placenta, kidney, brain, ovary, uterus and in several transformed cells.
數據庫鏈接：

KEGG: ocu:100009141

STRING: 9986.ENSOCUP00000001898

UniGene: Ocu.1889