TEQPQVVTEHPSMEAALTGPNASSHFWANYTFSDWQNFVGRRRYGAESQNPTVKALLIVA
YSFTIVFSLFGNVLVCHVIFKNQRMHSATSLFIVNLAVADIMITLLNTPFTLVRFVNSTW
VFGKGMCHVSRFAQYCSLHVSALTLTAIAVDRHQVIMHPLKPRISITKGVIYIAVIWVMA
TFFSLPHAICQKLFTFKYSEDIVRSLCLPDFPEPADLFWKYLDLATFILLYLLPLFIISV
AYARVAKKLWLCNTIGDVTTEQYLALRRKKKTTVKMLVLVVVLFALCWFPLNCYVLLLSS
KAIHTNNALYFAFHWFAMSSTCYNPFIYCWLNENFRVELKALLSMCQRPPKPQEDRLPSP
VPSFRVAWTEKSHGRRAPLPNHHLPSSQIQSGKTDLSSVEPVVAMS Note: The complete sequence may
include tag sequence, target protein sequence, linker sequence
and extra sequence that is translated with the protein sequence
for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant
protein is critical to your application, please explicitly
request the full and complete sequence of this protein before
ordering.
蛋白標簽:
N-terminal 10xHis-tagged
產品提供形式:
Liquid or
Lyophilized powder
Note: We will
preferentially ship the format that we have in stock, however,
if you have any special requirement for the format, please
remark your requirement when placing the order, we will prepare
according to your demand.
緩沖液:
Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
儲存條件:
Store at -20°C/-80°C upon receipt, aliquoting is
necessary for
mutiple use. Avoid repeated freeze-thaw cycles.
保質期:
The shelf life is related to many factors, storage
state,
buffer ingredients, storage temperature and the stability of the
protein
itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C.
The
shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期:
Basically, we can dispatch the products out in 1-3 working days
after receiving your orders. Delivery time may differ from different
purchasing way or location, please kindly consult your local
distributors for specific delivery time.
Note: All of our
proteins are default shipped with normal blue ice packs, if you
request to ship with dry ice, please communicate with us in
advance
and extra fees will be charged.
注意事項:
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Orphan receptor. Could be a neuropeptide Y receptor.
基因功能參考文獻:
this study identified a receptor for PEN in mouse hypothalamus and Neuro2A cellsit. It is GPR83. PMID: 27117253
Data indicate that the extracellular portion of G-protein coupled receptor 83 (GPR83) has a strong regulatory function on this receptor. PMID: 25516095
Gpr83 modulates ghrelin action and Gpr83 regulates systemic metabolism through other ghrelin-independent pathways. PMID: 23744028
GIR -/- mice show increased preference for sucrose, delayed acquisition of spatial learning and insensitivity to the anxiogenic effects of restraint stress. PMID: 23088626
GPR83 may participate in central thermoregulation and the central control of circulating adiponectin. PMID: 22560055
Gpr83 is critically involved in the peripheral conversion of Foxp3-negative to Foxp3-expressing regulatory T cells in vivo. PMID: 16785516
These results demonstrate that GPR83 is dispensable for Treg-cell development and function. PMID: 17893329