Recombinant Mouse Gap junction beta-4 protein (Gjb4)

in vitro E.coli expression system

中文名稱：

小鼠Gjb4重組蛋白
貨號：

CSB-CF009454MO
說明書：

MSDS Datasheet
規格：
來源：

in vitro E.coli expression system
其他：

產品詳情
產品評價
相關產品
靶點詳情

產品詳情

基因名：

Gjb4
Uniprot No.：

Q02738
別名：

Gjb4; Cxn-30.3; Gap junction beta-4 protein; Connexin-30.3; Cx30.3
種屬：

Mus musculus (Mouse)
蛋白長度：

Full length protein
表達區域：

1-266
氨基酸序列

MNWGFLQGILSGVNKYSTALGRIWLSVVFIFRVLVYVVAAEEVWDDDQKDFICNTKQPGC PNVCYDEFFPVSHVRLWALQLILVTCPSLLVVMHVAYREERERKHRLKHGPNAPALYSNL SKKRGGLWWTYLLSLIFKAAVDSGFLYIFHCIYKDYDMPRVVACSVTPCPHTVDCYIARP TEKKVFTYFMVVTAAICILLNLSEVVYLVGKRCMEVFRPRRRKASRRHQLPDTCPPYVIS KGGHPQDESVILTKAGMATVDAGVYP
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
蛋白標簽：

N-terminal 10xHis-tagged
產品提供形式：

Liquid or Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
緩沖液：

Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet & COA：

Please contact us to get it.

產品評價

靶點詳情

功能：

Structural component of gap junctions. Gap junctions are dodecameric channels that connect the cytoplasm of adjoining cells. They are formed by the docking of two hexameric hemichannels, one from each cell membrane. Small molecules and ions diffuse from one cell to a neighboring cell via the central pore.
基因功能參考文獻：
1. These indicate possible involvement of Cx30.3 in the rapid formation and/or decomposition of gap junctions; implying a functional relay between Cx30.3 and other systems such as adhesion proteins. PMID: 28205646
2. Cx30 regulates cell adhesion and migration; its modulation of glutamate transport occurs independently of its channel function and is mediated by morphological changes controlling insertion of astroglial processes into synaptic clefts. PMID: 24584052
3. Connexin30.3-deficient mice exhibit reduced behavioural responses to a vanilla scent. PMID: 17728008
4. Appears to be constitutively expressed in certain renal tubular segments and cells. PMID: 18649192
亞細胞定位：

Cell membrane; Multi-pass membrane protein. Cell junction, gap junction.
蛋白家族：

Connexin family, Beta-type (group I) subfamily
組織特異性：

Detected in cochlea (at protein level). Detected in cochlea. Expressed in skin.
數據庫鏈接：

KEGG: mmu:14621

STRING: 10090.ENSMUSP00000053307

UniGene: Mm.56906