Recombinant Chloride intracellular channel exc-4 (exc-4)

in vitro E.coli expression system

中文名稱：

秀麗隱桿線蟲exc-4重組蛋白
貨號：

CSB-CF837843CXY
說明書：

MSDS Datasheet
規(guī)格：
來源：

in vitro E.coli expression system
其他：

產(chǎn)品詳情
產(chǎn)品評價
相關(guān)產(chǎn)品
靶點詳情

產(chǎn)品詳情

基因名：

exc-4
Uniprot No.：

Q8WQA4
別名：

exc-4; Y105E8A.22; Chloride intracellular channel exc-4; Excretory canal abnormal protein 4
種屬：

Caenorhabditis elegans
蛋白長度：

full length protein
表達區(qū)域：

1-290
氨基酸序列

MAEAYQIQSNGDPQSKPLLELYVKASGIDARRIGADLFCQEFWMELYALYEIGVARVEVK TVNVNSEAFKKNFLGAQPPIMIEEEKELTYTDNREIEGRIFHLAKEFNVPLFEKDPSAEK RIENLYRNFKLFLRAKVEFDKGKKEPSRVEDLPAQIKVHYNRVCEQLSNIDQLLSERKSR YLLGNSMTEYDCELMPRLHHIRIIGLSLLGFDIPHNFTHLWAYILTAYRTAAFIESCPAD QDIIHHYKEQMNLFTNQRETLQSPTKTHTIPEKVLSDIRVKGLAPDVNVH
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
蛋白標簽：

N-terminal 10xHis-tagged
產(chǎn)品提供形式：

Liquid or Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
緩沖液：

Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質(zhì)期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet & COA：

Please contact us to get it.

產(chǎn)品評價

靶點詳情

功能：

May insert into membranes and form chloride ion channels. Involved in the formation of the excretory canal. Required to prevent cystic lumenal expansions in the excretory cell. Not required for formation of the initial tube, but is required for regulating the size of the tube lumen as it grows.
基因功能參考文獻：
1. The putative transmembrane (PTM) region thus provides both targeting information and Chloride intracellular channel functional specificity, possibly adapting GST-type proteins to function as ion channels. PMID: 16737711
2. distinguishing features of exc-4 structure determined from crystal structure are described PMID: 17985355
亞細胞定位：

Cytoplasm. Membrane; Single-pass membrane protein. Note=Exists both as soluble cytoplasmic protein and as membrane protein with probably a single transmembrane domain. Localizes to various tubular membranes in distinct cell types, including the lumenal membrane of the excretory tubes.
蛋白家族：

Chloride channel CLIC family
組織特異性：

Expressed in the secretory system, hypodermis, vulva, pharyngeal muscle, rectal gland, tubular rectal epithelium cells, and tubular neuronal support cells in the head and tail.
數(shù)據(jù)庫鏈接：

KEGG: cel:CELE_Y105E8A.22

STRING: 6239.Y105E8A.22

UniGene: Cel.24092