Recombinant Chicken Phosphatidylcholine:ceramide cholinephosphotransferase 1 (SGMS1)

in vitro E.coli expression system

中文名稱：

雞SGMS1重組蛋白
貨號：

CSB-CF745848CH
說明書：

MSDS Datasheet
規(guī)格：
來源：

in vitro E.coli expression system
其他：

產(chǎn)品詳情
產(chǎn)品評價
相關產(chǎn)品
靶點詳情

產(chǎn)品詳情

基因名：

SGMS1
Uniprot No.：

Q7T3T4
別名：

SGMS1; MOB; RCJMB04_29o9; Phosphatidylcholine:ceramide cholinephosphotransferase 1; Protein Mob; Sphingomyelin synthase 1
種屬：

Gallus gallus (Chicken)
蛋白長度：

full length protein
表達區(qū)域：

1-417
氨基酸序列

MSGRMKEVVSWSPEEVTNWLMENAVPEYCEPLKSFTGQDLINLTEEDFKKTPLSRVSSDS GQQLLHMIETLKMAHHIEAHKNGHVNGHIHVSVNNTAHENGFSSKTKLNGVPNGYKKEMI KIPMPEPERLQYPMEWGKTFLAFIYALFCFIFTTVTISVVHERVPPKEVQPPLPDAFFDR FDRVQWAFSICEINGMILVGLWLVQWLLLKYKSIISRRFFCIVCTLYLYRCITMYVTTLP VPGMHFKCSPKLFGDWESHLRRIMKLIAGGGLSITGSHNMCGDYLYSGHTVILTLTYLFI KEYSPRRLWWYHWLCWTLSMVGMFCILLAHDHYTVDVVVAYYITTRLFWWYHTMANQQVL KEASQTNLLARVWWYKPFQYFEKNVQGIVPRSYHWPFPWPVLHRGRQVKYSRLVNDT
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
蛋白標簽：

N-terminal 10xHis-tagged
產(chǎn)品提供形式：

Liquid or Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 668
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
緩沖液：

Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet & COA：

Please contact us to get it.

產(chǎn)品評價

靶點詳情

功能：

Sphingomyelin synthases synthesize the sphingolipid, sphingomyelin, through transfer of the phosphatidyl head group, phosphatidylcholine, on to the primary hydroxyl of ceramide. The reaction is bidirectional depending on the respective levels of the sphingolipid and ceramide. Golgi apparatus SMS1 directly and specifically recognizes the choline head group on the substrate, requiring two fatty chains on the choline-P donor molecule in order to be recognized efficiently as a substrate. Major form in macrophages. Required for cell growth in certain cell types. Suppresses BAX-mediated apoptosis and also prevents cell death in response to stimuli such as hydrogen peroxide, osmotic stress, elevated temperature and exogenously supplied sphingolipids. May protect against cell death by reversing the stress-inducible increase in levels of proapoptotic ceramide.
基因功能參考文獻：
1. Molecular cloning, sequence characterization, and tissue expression analysis of chicken sphingomyelin synthase 1 (SMS1).These data serve as a foundation for further insight into the chicken SMS1 gene. PMID: 21647613
亞細胞定位：

Golgi apparatus membrane; Multi-pass membrane protein.
蛋白家族：

Sphingomyelin synthase family
數(shù)據(jù)庫鏈接：

KEGG: gga:378907

STRING: 9031.ENSGALP00000040150

UniGene: Gga.2939