Recombinant Cat Follicle-stimulating hormone receptor (FSHR)

in vitro E.coli expression system

中文名稱(chēng)：

Recombinant Cat Follicle-stimulating hormone receptor(FSHR)
貨號(hào)：

CSB-CF702060CA
規(guī)格：
來(lái)源：

in vitro E.coli expression system
其他：

產(chǎn)品詳情
產(chǎn)品評(píng)價(jià)
相關(guān)產(chǎn)品
靶點(diǎn)詳情

產(chǎn)品詳情

基因名：

FSHR
Uniprot No.：

Q5GJ04
別名：

FSHR; Follicle-stimulating hormone receptor; FSH-R; Follitropin receptor
種屬：

Felis catus (Cat) (Felis silvestris catus)
蛋白長(zhǎng)度：

Full Length of Mature Protein
表達(dá)區(qū)域：

18-695
氨基酸序列

CHHRICHCWHRVFLCQESKVTEIPSDLPRNAVELRFVLTKLRVIPKGAFSGFGDLEKIEI SQNDVLEVIEANVFFNLSKLHEIRIEKANNLLYIDTDAFQNLPNLRYLLISNTGIKHFPA VHKIQSLQKVLLDIQDNINIHTVERNSFMGLSFESMILWLNKNGIQEIHNCAFNGTQLDE LNLSDNINLEELPNDVFQGASGPVILDISRTRIHSLPSYGLENIKKLRAKSTYNLKKLPS LDKFVALMEASLTYPSHCCAFANWRRPISELHPICNKSILRQEVDDMTQARGQRVSLAED EESSYTKGFDMMYSEFDYDLCNEVVDVTCSPKPDAFNPCEDIMGYDILRVLIWFISILAI TGNIIVLMILITSQYKLTVPRFLMCNLAFADLCIGIYLLLIASVDIYTKSQYHNYAIDWQ TGAGCDAAGFFTVFASELSVYTLTVITLERWHTITHAMQLECKVQLRHAAIIMLLGWIFA FMVALFPIFGISSYMKVSICLPMDIDSPLSQLYVMSLLVLNVLAFVVICCCYAHIYLTVR NPNIVSSSSDTKIAKRMAMLIFTDFLCMAPISFFAISASLKVPLITVSKSKILLVLFYPI NSCANPFLYAIFTKNFRRDFFILLSKFGCYEVQAQTYRSETSSTAHNFHPRNGHCPPAPR VTNSSNYILIPLRHLAKN
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
蛋白標(biāo)簽：

N-terminal 10xHis-tagged
產(chǎn)品提供形式：

Liquid or Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
緩沖液：

Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
儲(chǔ)存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質(zhì)期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項(xiàng)：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet & COA：

Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

功能：

G protein-coupled receptor for follitropin, the follicle-stimulating hormone. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways.
基因功能參考文獻(xiàn)：
1. No differences in the ovarian expression of FSHR mRNA, LHR protein or mRNA were found between the pre-pubertal and adult cats, but significantly lower FSHR protein expression was found in pre-pubertal cats compared to adult luteal cats. PMID: 28402061
2. Results describe the expression of follicle stimulating hormone and luteinizing hormone receptors during follicular growth in the domestic cat ovary. PMID: 17219419
亞細(xì)胞定位：

Cell membrane; Multi-pass membrane protein.
蛋白家族：

G-protein coupled receptor 1 family, FSH/LSH/TSH subfamily
數(shù)據(jù)庫(kù)鏈接：

KEGG: fca:554348

STRING: 9685.ENSFCAP00000001126