Recombinant Arabidopsis thaliana Aluminum-activated malate transporter 12 (ALMT12)

in vitro E.coli expression system

中文名稱：

Recombinant Arabidopsis thaliana Aluminum-activated malate transporter 12(ALMT12)
貨號：

CSB-CF526193DOA
說明書：

MSDS Datasheet
規格：
來源：

in vitro E.coli expression system
其他：

產品詳情
產品評價
相關產品
靶點詳情

產品詳情

基因名：

ALMT12
Uniprot No.：

O49696
別名：

ALMT12; QUAC1; At4g17970; T6K21.150; Aluminum-activated malate transporter 12; AtALMT12; Quick anion channel 1
種屬：

Arabidopsis thaliana (Mouse-ear cress)
蛋白長度：

full length protein
表達區域：

1-560
氨基酸序列

MSNKVHVGSLEMEEGLSKTKWMVLEPSEKIKKIPKRLWNVGKEDPRRVIHALKVGLSLTL VSLLYLMEPLFKGIGSNAIWAVMTVVVVLEFSAGATLCKGLNRGLGTLIAGSLAFFIEFV ANDSGKVLRAIFIGTAVFIIGAAATYIRFIPYIKKNYDYGVVIFLLTFNLITVSSYRVDS VINIAHDRFYTIAVGCGICLFMSLLVFPIWSGEDLHKTTVGKLQGLSRSIEACVDEYFEE KEKEKTDSKDRIYEGYQAVLDSKSTDETLALYANWEPRHTLRCHRFPCQQYVKVGAVLRQ FGYTVVALHGCLQTEIQTPRSVRALFKDPCVRLAGEVCKALTELADSISNHRHCSPEILS DHLHVALQDLNSAIKSQPKLFLGSNLHRHNNKHQNGSISNNKHHQRNSSNSGKDLNGDVS LQNTETGTRKITETGSRQGQNGAVSLSSFRTDTSALMEYRRSFKNSNSEMSAAGERRMLR PQLSKIAVMTSLEFSEALPFAAFASLLVEMVARLDNVIEEVEELGRIASFKEYDNKRDQT ADDVRCENPANVTISVGAAE
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
蛋白標簽：

N-terminal 10xHis-tagged
產品提供形式：

Liquid or Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
緩沖液：

Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet & COA：

Please contact us to get it.

產品評價

靶點詳情

功能：

Malate-sensitive anion transporter permeable to chloride, nitrate, sulfate and malate. Involved in dark-, CO(2)-, abscisic acid- and water-deficient-induced stomatal closure. Belongs to the R-type anion channels.
基因功能參考文獻：
1. ALMT12 role in drought induced stomatal closure PMID: 28446637
2. QUAC1, an R-type anion channel responsible for the release of malate from guard cells, is essential for efficient stomatal closure and plays a role in mesophyll conductance. PMID: 26542441
3. In the presence of abscissic acid, OST1 is able to phosphorylate/activate the plant anion channels QUAC1 and SLAC1, leading to stomatal closure.[QUAC1] PMID: 23452338
4. The cytosolic C-terminus is involved in the voltage-dependent gating mechanism of QUAC1. PMID: 23314055
5. Activity of heterologously expressed AtALMT12 depends on extracellular malate. Thereby this key metabolite and osmolite of guard cells shifts the threshold for voltage activation of AtALMT12 towards more hyperpolarized potentials. PMID: 20626656
6. AtALMT12 is a novel class of anion transporter involved in stomatal closure. PMID: 20154005
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亞細胞定位：

Cell membrane; Multi-pass membrane protein. Note=PubMed:20626656 indicates also a not confirmed endomembrane localization.
蛋白家族：

Aromatic acid exporter (TC 2.A.85) family
組織特異性：

Expressed in roots, stems, leaves, flowers and pollen. Mainly detected in the roots vascular stele and in the leaves guard cells.
數據庫鏈接：

KEGG: ath:AT4G17970

STRING: 3702.AT4G17970.1

UniGene: At.2053