Recombinant Xenopus laevis Protein Wnt-1 (wnt1)

中文名稱：

有爪蟾蜍wnt1重組蛋白
貨號：

CSB-YP320718XBE
規格：
來源：

Yeast
其他：

中文名稱：

有爪蟾蜍wnt1重組蛋白
貨號：

CSB-EP320718XBE
規格：
來源：

E.coli
其他：

中文名稱：

有爪蟾蜍wnt1重組蛋白
貨號：

CSB-EP320718XBE-B
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

有爪蟾蜍wnt1重組蛋白
貨號：

CSB-BP320718XBE
規格：
來源：

Baculovirus
其他：

中文名稱：

有爪蟾蜍wnt1重組蛋白
貨號：

CSB-MP320718XBE
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

wnt1
Uniprot No.：

P10108
別名：

wnt1; int1Protein Wnt-1; XWnt-1; XInt-1
種屬：

Xenopus laevis (African clawed frog)
蛋白長度：

Full Length of Mature Protein
表達區域：

20-371
氨基酸序列

S LSNTIAVNNS GKWWGIVNVA SAGNVLPGSD ARPVPLVLDP SLQLLSRQKR LIRQNPGILQ SITRGLHSAI RECKWHFRNR RWNCPTGTGN QVFGKIINRG CRETAFVFAI TSAGVTHSVA RSCSEGSIES CSCDYRRRGP GGPDWHWGGC SDNIEFGRFI GREFVDSSER GRDLKYLVNL HNNQAGRLTV LTEMRQECKC HGMSGSCSLR TCWMRLPPFR SVGDALKDRF DGASKVTYSN NGSNRWGSRS DPPHLEPENP THALPSSQDL VYFEKSPNFC SPSEKNGTPG TTGRICNSTS LGLDGCELLC CGRGYRSLAE KVTERCHCTF NWCCHVTCLN CTSSQIVHEC L
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Ligand for members of the frizzled family of seven transmembrane receptors. Acts in the canonical Wnt signaling pathway by promoting beta-catenin-dependent transcriptional activation. Plays an important role in patterning during embryonic development. Plays an essential role in the development of the embryonic brain and central nervous system (CNS). Has a role in osteoblast function, bone development and bone homeostasis.
基因功能參考文獻：
1. maternal Wnt/STOP signaling, but not beta-catenin signaling, has a role in cleavage after fertilization and cell cycle progression PMID: 25901317
2. sfrp1 promotes cardiomyocyte differentiation in Xenopus via negative-feedback regulation of Wnt signalling. PMID: 23482489
3. Data show taht combined Wnt and Nodal signaling synergistically activates transcription of Spemann organizer genes. PMID: 22627292
4. The authors propose that these dual functions of DP1 can promote and stabilize biphasic Wnt-on and Wnt-off states in response to a gradual gradient of Wnt/beta-catenin signalling to determine differential cell fates. PMID: 22773187
亞細胞定位：

Secreted, extracellular space, extracellular matrix. Secreted.
蛋白家族：

Wnt family
組織特異性：

At neurula in anterior neural fold; at tailbud in dorsal midline of midbrain.
數據庫鏈接：

KEGG: xla:373578

UniGene: Xl.29