Recombinant Xenopus laevis Homeobox protein meis3-A (meis3-a)

中文名稱：

有爪蟾蜍meis3-a重組蛋白
貨號：

CSB-YP736023XBE
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

有爪蟾蜍meis3-a重組蛋白
貨號：

CSB-EP736023XBE
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

有爪蟾蜍meis3-a重組蛋白
貨號：

CSB-EP736023XBE-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

有爪蟾蜍meis3-a重組蛋白
貨號：

CSB-BP736023XBE
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

有爪蟾蜍meis3-a重組蛋白
貨號：

CSB-MP736023XBE
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

meis3-a
Uniprot No.：

Q5U4X3
別名：

meis3-a; meis3; Homeobox protein meis3-A; XMeis3
種屬：

Xenopus laevis (African clawed frog)
蛋白長度：

full length protein
表達區域：

1-453
氨基酸序列

MAQRYDEMLH YPTLDGMPLA GFGDAHTGRA LQHHSLSQSA PYGSTGAGHR VPMPPGMGSN DGLKREKDEI YGHPLFPLLA LVFEKCELAT CSPRDNSGSF PGGDVCSSDS FNEDIAVFAK QVRTEKPLFS SNPELDSLMI QAIQVLRFHL LELEKVHDLC DNFCHRYITC LKGKMPIDLV IDDRDGSSKS DLEDFTGSCT SLSDQNNSWL RDHDETGSAH SGTPGPSSGG LASQSGDNSS EQGDCMDNSV ASPSTGDDDD LDRDKKRNKK RGIFPKVATN IMRAWLFQHL SHPYPSEEQK KQLAQDTGLT ILQVNNWFIN ARRRIVQPMI DQSNRTGQGG APYSPDGQNM GGYVMDGQQH MGIRPPGFQG IPGDYTAAPS TMPMGFPPAG YTPAIPPHSA GLRHGPSLHS YLPGHPHHAS MILPAGASPH HLVSAQSPAD ALLNGQNIDI HAH
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Caudalizing protein which is required to pattern the anterior/posterior (A/P) axis during central nervous system (CNS) formation. Inhibits anterior neural expression and acts as a transcriptional activator to induce posterior neural gene expression. Maintains a proper A/P balance required for hindbrain formation by activating the FGF/MAPK pathway, which modulates the planar cell polarity (PCP) pathway. Interacts with retinoid signaling during hindbrain patterning.
基因功能參考文獻：
1. Synergy between XMeis3 and Hoxd1 in Hoxd1 autoregulation in mesoderm during gastrulation, is shown. PMID: 21464931
2. XMeis3 protein knock down also causes a loss of primary neuron and neural crest cell lineages, without altering expression of Zic, Sox or Pax3 genes. PMID: 19944089
3. XMeis3 activates FGF/MAP-kinase signaling, which then modulates the PCP pathway. PMID: 14660437
4. XMeis3 protein appears crucial for initial hindbrain induction, whereas Retinoic Acid signaling defines the spatial limits of hindbrain gene expression by modifying XMeis3 protein activity PMID: 15196951
亞細胞定位：

Nucleus.
蛋白家族：

TALE/MEIS homeobox family
組織特異性：

In early-mid neurula stages, expressed in a single stripe in the neural plate. By neurula/early-tailbud stages, expression is localized to rhombomeres r2, r3 and r4 and the anterior spinal cord. Some ventral expression was also detected in posterior rhomb
數據庫鏈接：

KEGG: xla:398093

UniGene: Xl.452