Recombinant Vaccinia virus Ribonucleoside-diphosphate reductase small chain (VACWR043)

中文名稱：

Recombinant Vaccinia virus Ribonucleoside-diphosphate reductase small chain (VACWR043)
貨號：

CSB-YP320834VAI
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

Recombinant Vaccinia virus Ribonucleoside-diphosphate reductase small chain (VACWR043)
貨號：

CSB-EP320834VAI
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

Recombinant Vaccinia virus Ribonucleoside-diphosphate reductase small chain (VACWR043)
貨號：

CSB-EP320834VAI-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

Recombinant Vaccinia virus Ribonucleoside-diphosphate reductase small chain (VACWR043)
貨號：

CSB-BP320834VAI
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

Recombinant Vaccinia virus Ribonucleoside-diphosphate reductase small chain (VACWR043)
貨號：

CSB-MP320834VAI
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

VACWR043
Uniprot No.：

P11158
別名：

VACWR043; F4L; Ribonucleoside-diphosphate reductase small chain; EC 1.17.4.1; Ribonucleotide reductase small subunit
種屬：

Vaccinia virus (strain Western Reserve) (VACV) (Vaccinia virus (strain WR))
蛋白長度：

full length protein
表達區域：

1-319
氨基酸序列

MEPILAPNPN RFVIFPIQYY DIWNMYKKAE ASFWTVEEVD ISKDINDWNK LTPDEKYFIK HVLAFFAASD GIVNENLAER FCTEVQITEA RCFYGFQMAI ENIHSEMYSL LIDTYVKDSN EKNYLFNAIE TMPCVKKKAD WAQKWIHDSA GYGERLIAFA AVEGIFFSGS FASIFWLKKR GLMPGLTFSN ELISRDEGLH CDFACLMFKH LLHPPSEETV RSIITDAVSI EQEFLTAALP VKLIGMNCEM MKTYIEFVAD RLISELGFKK IYNVTNPFDF MENISLEGKT NFFEKRVGEY QKMGVMSQED NHFSLDVDF
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Ribonucleoside-diphosphate reductase holoenzyme provides the precursors necessary for viral DNA synthesis. Allows virus growth in non-dividing cells. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
基因功能參考文獻：
1. The F4L-deleted vaccinia viruses are highly attenuated in normal tissues, and since cancer cells commonly express elevated cell-cycle-regulated small subunit of ribonucleotide reductase (RRM2) levels, have tumor-selective replication and cell killing. PMID: 28289079
2. poxvirus R2 subunits form functional complexes with host R1 subunits to provide sufficient dNTPs for viral replication. PMID: 20628573
蛋白家族：

Ribonucleoside diphosphate reductase small chain family
數據庫鏈接：

KEGG: vg:3707500