Recombinant Staphylococcus aureus Enterotoxin type E (entE)

文獻引用 (1)

中文名稱：

金黃色釀膿葡萄球菌entE重組蛋白
貨號：

CSB-YP320170FKZ
說明書：

MSDS Datasheet
規格：

￥2616
圖片：
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

Based on the SEQUEST from database of Yeast host and target protein, the LC-MS/MS Analysis result of CSB-YP320170FKZ could indicate that this peptide derived from Yeast-expressed Staphylococcus aureus entE.

Based on the SEQUEST from database of Yeast host and target protein, the LC-MS/MS Analysis result of CSB-YP320170FKZ could indicate that this peptide derived from Yeast-expressed Staphylococcus aureus entE.
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靶點詳情

產品詳情

純度：

Greater than 90% as determined by SDS-PAGE.
基因名：

entE
Uniprot No.：

P12993
別名：

entEEnterotoxin type E; SEE
種屬：

Staphylococcus aureus
蛋白長度：

Full Length of Mature Protein
來源：

Yeast
分子量：

28.4kDa
表達區域：

28-257aa
氨基酸序列

SEEINEKDLRKKSELQRNALSNLRQIYYYNEKAITENKESDDQFLENTLLFKGFFTGHPWYNDLLVDLGSKDATNKYKGKKVDLYGAYYGYQCAGGTPNKTACMYGGVTLHDNNRLTEEKKVPINLWIDGKQTTVPIDKVKTSKKEVTVQELDLQARHYLHGKFGLYNSDSFGGKVQRGLIVFHSSEGSTVSYDLFDAQGQYPDTLLRIYRDNKTINSENLHIDLYLYTT
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
蛋白標簽：

N-terminal 6xHis-tagged
產品提供形式：

Liquid or Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
緩沖液：

If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol.
Note: If you have any special requirement for the glycerol content, please remark when you place the order.
If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
產品描述：

A DNA sequence corresponding to 28-257aa of the Staphylococcus aureus Enterotoxin type E (entE) was expressed with an N-terminal 6xHis-tag in the yeast. The resulting protein is a full-length of the mature entE protein. It underwent the validation of LC-MS/MS analysis. Its purity reaches up to 90% determined by SDS-PAGE. It can be used to produce specific antibodies. This recombinant entE protein may also find uses in the studies of entE-associated cell biology.

As one of the most important microorganisms, Staphylococcus aureus causes various human diseases by secreting virulence factors staphylococcal superantigens (SAgs). EntE, also known as SEE, is one of the toxic SAgs, which can cross-link the T cell receptor (TCR) and major histocompatibility complex class II, triggering a massive T cell activation and hence disease. Depending on the dose and route of exposure, SEE and other SEs can cause food poisoning, acute and fatal respiratory distress, and toxic shock.
Datasheet & COA：

Please contact us to get it.

引用文獻

The CTLA‐4 immune checkpoint protein regulates PD‐L1: PD‐1 interaction via transendocytosis of its ligand CD80 A Kennedy,The EMBO journal,2023

產品評價

靶點詳情

功能：

Staphylococcal enterotoxin that activates the host immune system by binding as unprocessed molecules to major histocompatibility (MHC) complex class II and T-cell receptor (TCR) molecules. In turn, this ternary complex activates a large number of T-lymphocytes initiating a systemic release of proinflammatory cytokines. Causes also the intoxication staphylococcal food poisoning syndrome.
亞細胞定位：

Secreted.
蛋白家族：

Staphylococcal/streptococcal toxin family