Recombinant Sheep Pituitary-specific positive transcription factor 1 (POU1F1)

中文名稱：

綿羊POU1F1重組蛋白
貨號：

CSB-YP018391SH
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

綿羊POU1F1重組蛋白
貨號：

CSB-EP018391SH
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

綿羊POU1F1重組蛋白
貨號：

CSB-EP018391SH-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

綿羊POU1F1重組蛋白
貨號：

CSB-BP018391SH
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

綿羊POU1F1重組蛋白
貨號：

CSB-MP018391SH
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

POU1F1
Uniprot No.：

P79364
別名：

POU1F1; PIT-1; PIT1; Pituitary-specific positive transcription factor 1; PIT-1; Growth hormone factor 1; GHF-1
種屬：

Ovis aries (Sheep)
蛋白長度：

Full length protein
表達區域：

1-291
氨基酸序列

MSCQPFTSTD TFIPLNSESS ATLPLIMHPS AAECLPVSNH ATNVMSTATG LHYSVPSCHY GNQSSTYGVM AGSLTPCLYE FPDHTLSHGF PPMHQPLLSE DPTAADFKQE LRRKSKLIEE PIDMDSPEIR ELEKFANEFK VRRIKLGYTQ TNVGEALAAV HGSEFSQTTI CRFENLQLSF KNACKLKAIL FKWLEEAEQV GALYNEKVGA NERKRKRRTT ISIAAKDALE RHFGEQNKPS SQEILRMAEE LNLEKEVVRV WFCNRRQREK RVKTSLNQSL FPNSKEHLEC R
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Transcription factor involved in the specification of the lactotrope, somatotrope, and thyrotrope phenotypes in the developing anterior pituitary. Activates growth hormone and prolactin genes. Specifically binds to the consensus sequence 5'-TAAAT-3'.
基因功能參考文獻：
1. Weaning weight of Lori-Bakhtiari and Zel sheep breeds were affected by polymorphism in exon 3 of POU1F1 gene, suggesting that this polymorphism can be used as a molecular marker for this trait. PMID: 24965143
2. it can be assumed that exon 3 POU1F1 in these Iranian indigenous sheep breeds has high variability and the SNP observed in this study are associated with weaning weight trait PMID: 25572243
3. Molecular cloning, sequencing and characterization of POU1F1 PMID: 16636924
4. isolated three additional splicing variants: POU1F1-beta, with a 78 bp insert in the trans-activation domain; POU1F1-gamma that lacks exon 3 and POU1F1-delta that lacks exons 3, 4 and 5 PMID: 16942842
亞細胞定位：

Nucleus.
蛋白家族：

POU transcription factor family, Class-1 subfamily
數據庫鏈接：

KEGG: oas:443370

UniGene: Oar.781