Recombinant Schizosaccharomyces pombe Serine/threonine-protein kinase chk1 (chk1)

中文名稱：

Recombinant Schizosaccharomyces pombe Serine/threonine-protein kinase chk1(chk1)
貨號：

CSB-YP005338SXV
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

Recombinant Schizosaccharomyces pombe Serine/threonine-protein kinase chk1(chk1)
貨號：

CSB-EP005338SXV
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

Recombinant Schizosaccharomyces pombe Serine/threonine-protein kinase chk1(chk1)
貨號：

CSB-EP005338SXV-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

Recombinant Schizosaccharomyces pombe Serine/threonine-protein kinase chk1(chk1)
貨號：

CSB-BP005338SXV
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

Recombinant Schizosaccharomyces pombe Serine/threonine-protein kinase chk1(chk1)
貨號：

CSB-MP005338SXV
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

chk1
Uniprot No.：

P34208
別名：

chk1; rad27; SPCC1259.13Serine/threonine-protein kinase chk1; EC 2.7.11.1; Checkpoint kinase 1
種屬：

Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
蛋白長度：

full length protein
表達區域：

1-496
氨基酸序列

MAQKLDNFPY HIGREIGTGA FASVRLCYDD NAKIYAVKFV NKKHATSCMN AGVWARRMAS EIQLHKLCNG HKNIIHFYNT AENPQWRWVV LEFAQGGDLF DKIEPDVGID EDVAQFYFAQ LMEGISFMHS KGVAHRDLKP ENILLDYNGN LKISDFGFAS LFSYKGKSRL LNSPVGSPPY AAPEITQQYD GSKVDVWSCG IILFALLLGN TPWDEAISNT GDYLLYKKQC ERPSYHPWNL LSPGAYSIIT GMLRSDPFKR YSVKHVVQHP WLTSSTPFRT KNGNCADPVA LASRLMLKLR IDLDKPRLAS SRASQNDSGF SMTQPAFKKN DQKELDRVEV YGALSQPVQL NKNIDVTEIL EKDPSLSQFC ENEGFIKRLA KKAKNFYEIC PPERLTRFYS RASRETIIDH LYDSLRLLAI SVTMKYVRNQ TILYVNLHDK RKCLLQGVIE LTNLGHNLEL INFIKRNGDP LEWRKFFKNV VSSIGKPIVL TDVSQN
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Serine/threonine-protein kinase which is required for checkpoint-mediated cell cycle arrest and activation of DNA repair in response to the presence of DNA damage or unreplicated DNA. May also negatively regulate cell cycle progression during unperturbed cell cycles. Binds to and phosphorylates CDC25. This leads to negative regulation of CDC25 and prevents mitotic entry.
亞細胞定位：

Nucleus.
蛋白家族：

Protein kinase superfamily, CAMK Ser/Thr protein kinase family, NIM1 subfamily
數據庫鏈接：

KEGG: spo:SPCC1259.13

STRING: 4896.SPCC1259.13.1