Recombinant Salmonella typhimurium Transcriptional regulator slyA (slyA)

中文名稱：

鼠傷寒沙門菌slyA重組蛋白
貨號：

CSB-YP336764SXB
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

鼠傷寒沙門菌slyA重組蛋白
貨號：

CSB-EP336764SXB
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

鼠傷寒沙門菌slyA重組蛋白
貨號：

CSB-EP336764SXB-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

鼠傷寒沙門菌slyA重組蛋白
貨號：

CSB-BP336764SXB
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

鼠傷寒沙門菌slyA重組蛋白
貨號：

CSB-MP336764SXB
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

slyA
Uniprot No.：

P40676
別名：

slyA; STM1444; Transcriptional regulator SlyA; Cytolysin SlyA; Salmolysin
種屬：

Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
蛋白長度：

full length protein
表達區域：

1-144
氨基酸序列

MESPLGSDLA RLVRIWRALI DHRLKPLELT QTHWVTLHNI HQLPPDQSQI QLAKAIGIEQ PSLVRTLDQL EDKGLISRQT CASDRRAKRI KLTEKADALI AEMEEVIHKT RGEILAGISS EEIELLIKLI AKLEHNIMEL HSHD
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Transcription regulator that can specifically activate or repress expression of target genes. Required for virulence and survival in the macrophage environment. Probably activates expression of ispA, xseB genes, and of omp operon.
基因功能參考文獻：
1. SlyA and other MarR global regulators rely more on indirect readout of DNA sequence to exert control over many genes PMID: 21550983
2. Residues Leu-63, Val-64, Arg-65, Leu-67, Leu-70, Arg-86 and Lys-88 are required for DNA binding, and residues Leu-12 and Leu-126 in the alpha-helices of the N- and C-terminal regions are required for dimer formation. PMID: 17259627
3. Systematic mutational analysis shows that no single base pair in the palindromic SlyA operator sequence is essential for DNA binding, and identifies amino acid residues required to allow SlyA to recognise DNA. PMID: 19204896
蛋白家族：

SlyA family
數據庫鏈接：

KEGG: stm:STM1444

STRING: 99287.STM1444