Recombinant Saccharomyces cerevisiae NAD-dependent histone deacetylase HST3 (HST3)

中文名稱：

釀酒酵母HST3重組蛋白
貨號：

CSB-YP346476SVG
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

釀酒酵母HST3重組蛋白
貨號：

CSB-EP346476SVG
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

釀酒酵母HST3重組蛋白
貨號：

CSB-EP346476SVG-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

釀酒酵母HST3重組蛋白
貨號：

CSB-BP346476SVG
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

釀酒酵母HST3重組蛋白
貨號：

CSB-MP346476SVG
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

HST3
Uniprot No.：

P53687
別名：

HST3; YOR025W; OR26.15; NAD-dependent histone deacetylase HST3; EC 2.3.1.286; Homologous to SIR2 protein 3; Regulatory protein SIR2 homolog 3
種屬：

Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
蛋白長度：

full length protein
表達區域：

1-447
氨基酸序列

MTSVSPSPPA SRSGSMCSDL PSSLQTEKLA HIIGLDADDE VLRRVTKQLS RSRRIACLTG AGISCNAGIP DFRSSDGLYD LVKKDCSQYW SIKSGREMFD ISLFRDDFKI SIFAKFMERL YSNVQLAKPT KTHKFIAHLK DRNKLLRCYT QNIDGLEESI GLTLSNRKLP LTSFSSHWKN LDVVQLHGDL KTLSCTKCFQ TFPWSRYWSR CLRRGELPLC PDCEALINKR LNEGKRTLGS NVGILRPNIV LYGENHPSCE IITQGLNLDI IKGNPDFLII MGTSLKVDGV KQLVKKLSKK IHDRGGLIIL VNKTPIGESS WHGIIDYQIH SDCDNWVTFL ESQIPDFFKT QDQIKKLRQL KREASDLRKQ MKAQKDSIGT PPTTPLRTAQ GIDIQGNNEL NTKIKSLNTV KRKILSPENS SEEDEEENLD TRKRAKIRPT FGDNQAS
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

NAD-dependent histone deacetylase, which contributes together with HST4 to histone H3 'Lys-56' deacetylation, regulation of telomeric silencing, proper cell cycle progression, DNA damage control, DNA recombination, and genomic maintenance.
基因功能參考文獻：
1. That acetylation of Histone H3 by Hst3 takes place during checkpoint regulation was determined. PMID: 16818235
2. cells lacking Hst3p in which H3 K56 is constitutively hyperacetylated, exhibit hallmarks of spontaneous DNA damage PMID: 18579506
亞細胞定位：

Cytoplasm. Nucleus.
蛋白家族：

Sirtuin family, Class I subfamily
數據庫鏈接：

KEGG: sce:YOR025W

STRING: 4932.YOR025W