Recombinant Saccharomyces cerevisiae J-type co-chaperone JAC1, mitochondrial (JAC1)

中文名稱：

釀酒酵母JAC1重組蛋白
貨號：

CSB-YP345660SVG
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

釀酒酵母JAC1重組蛋白
貨號：

CSB-EP345660SVG
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

釀酒酵母JAC1重組蛋白
貨號：

CSB-EP345660SVG-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

釀酒酵母JAC1重組蛋白
貨號：

CSB-BP345660SVG
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

釀酒酵母JAC1重組蛋白
貨號：

CSB-MP345660SVG
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

JAC1
Uniprot No.：

P53193
別名：

JAC1; SEO2; YGL018CJ-type co-chaperone JAC1; mitochondrial; J-type accessory chaperone 1
種屬：

Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
蛋白長度：

full length protein
表達區域：

11-184
氨基酸序列

TSTFYELFPK TFPKKLPIWT IDQSRLRKEY RQLQAQHHPD MAQQGSEQSS TLNQAYHTLK DPLRRSQYML KLLRNIDLTQ EQTSNEVTTS DPQLLLKVLD IHDELSQMDD EAGVKLLEKQ NKERIQDIEA QLGQCYNDKD YAAAVKLTVE LKYWYNLAKA FKDWAPGKQL EMNH
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Co-chaperone required for the assembly of iron-sulfur (Fe/S) clusters in mitochondria. Stimulates the ATPase activity of its specialized Hsp70 chaperone partner SSQ1, to mediate the transfer of iron-sulfur clusters from ISU1 to GRX5. Binds to the substrate protein ISU1 and targets it to SSQ1.
基因功能參考文獻：
1. Isu is a substrate of the Lon-type protease and that it is protected from degradation by Jac1, the J-protein Hsp70 cochaperone that functions in cluster transfer from Isu. Jac1 variants known to be defective in interaction with Isu were also defective in protecting Isu from degradation. PMID: 26842892
2. Studied the structure and dynamics of the yeast Isu1-Jac1 complex. PMID: 25973573
3. Jac1:Isu1 interaction plays an indispensable role in the essential process of mitochondrial Fe-S cluster biogenesis PMID: 22306468
4. analysis of the interaction between Jac1p and the scaffold for Fe-S cluster biogenesis, Isu1p PMID: 16551614
亞細胞定位：

Mitochondrion matrix.
蛋白家族：

HscB family
數據庫鏈接：

KEGG: sce:YGL018C

STRING: 4932.YGL018C