Recombinant Saccharomyces cerevisiae Chromatin structure-remodeling complex subunit RSC2 (RSC2), partial

中文名稱：

釀酒酵母RSC2重組蛋白
貨號：

CSB-YP312369SVG
規格：
來源：

Yeast
其他：

中文名稱：

釀酒酵母RSC2重組蛋白
貨號：

CSB-EP312369SVG
規格：
來源：

E.coli
其他：

中文名稱：

釀酒酵母RSC2重組蛋白
貨號：

CSB-EP312369SVG-B
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

釀酒酵母RSC2重組蛋白
貨號：

CSB-BP312369SVG
規格：
來源：

Baculovirus
其他：

中文名稱：

釀酒酵母RSC2重組蛋白
貨號：

CSB-MP312369SVG
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
相關產品
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

RSC2
Uniprot No.：

Q06488
別名：

RSC2; YLR357W; L9638.1; Chromatin structure-remodeling complex subunit RSC2; RSC complex subunit RSC2; Remodel the structure of chromatin complex subunit 2
種屬：

Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
蛋白長度：

Partial
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Component of the chromatin structure remodeling complex (RSC), which is involved in transcription regulation and nucleosome positioning. RSC is responsible for the transfer of a histone octamer from a nucleosome core particle to naked DNA. The reaction requires ATP and involves an activated RSC-nucleosome intermediate. Remodeling reaction also involves DNA translocation, DNA twist and conformational change. As a reconfigurer of centromeric and flanking nucleosomes, RSC complex is required both for proper kinetochore function in chromosome segregation and, via a PKC1-dependent signaling pathway, for organization of the cellular cytoskeleton. This subunit is involved in meiotic sporulation through regulating IME2 expression, and is also essential for 2-micron plasmid maintenance and for normal REP1 protein localization.
基因功能參考文獻：
1. Results show that H4 acetylation by the NuA4 complex and RSC2 are both required for gap-induced sister chromatid recombination. PMID: 25132173
2. This study uncovered a direct interaction between the Rsc2 BAH domain and histone H3 and led to the identification of an interaction interface that is conserved in a subset of Rsc-like BAH domains. PMID: 23907388
3. Data show that RSC1 and RSC2 are haploinsufficient for spore formation in a smk1 hypomorph. PMID: 15302824
4. RSC2 may function through the tRNA element to restric the spread of silencing PMID: 16079223
亞細胞定位：

Nucleus. Note=Localizes to centromeric and flanking chromatin. Association with these loci is dependent on STH1.
蛋白家族：

RSC1 family
數據庫鏈接：

KEGG: sce:YLR357W

STRING: 4932.YLR357W