Recombinant Rat Translation initiation factor eIF-2B subunit delta (Eif2b4)

中文名稱：

大鼠Eif2b4重組蛋白
貨號：

CSB-YP723561RA
規格：
來源：

Yeast
其他：

中文名稱：

大鼠Eif2b4重組蛋白
貨號：

CSB-EP723561RA
規格：
來源：

E.coli
其他：

中文名稱：

大鼠Eif2b4重組蛋白
貨號：

CSB-EP723561RA-B
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

大鼠Eif2b4重組蛋白
貨號：

CSB-BP723561RA
規格：
來源：

Baculovirus
其他：

中文名稱：

大鼠Eif2b4重組蛋白
貨號：

CSB-MP723561RA
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

Eif2b4
Uniprot No.：

Q63186
別名：

Eif2b4; Eif2bd; Translation initiation factor eIF-2B subunit delta; eIF-2B GDP-GTP exchange factor subunit delta
種屬：

Rattus norvegicus (Rat)
蛋白長度：

Full Length of Mature Protein
表達區域：

2-524
氨基酸序列

AAVAVAVRE ESRSEMKTEL SPRPGAAGRE LTQEEKLQLR KEKKQQKKKR KEEKGADQEI GSAVSAAQRQ DPVRELQGTG SQLGGTTGEK LPAGRSKAEL RAERRAKQEA ERALKQARKG EQGGPSPQAC PSTAGEATSG VKRVPEHTQA DDPTLLRRLL RKPDRQQVPT RKDYGSKVSL FSHLPQYSRQ SSLTQYMSIP SSVIHPAMVR LGLQYSQGLV SGSNARCIAL LHALQQVIQD YTTPPNEELS RDLVNKLKPY ISFLTQCRPM SASMCNAIKF FNKEVTGMSS SKREEEAKSE LKEAIDRYVQ EKIVLASQAI SRFASKKISD GDVILVYGCS SLVSRILQEA WVEGRRFRVV VVDSRPRLEG RHMLHCLVRA GVPTSYLLIP AASYVLPEVS KVLLGAHALL ANGSVMSRVG TAQLALVARA HNVPVLVCCE TYKFCERVQT DAFVSNELDD PDDLQCKRGD QVTLANWQNN SSLRLLNLVY DVTPPELVDL VITELGMIPC SSVPVVLRVK SSDQ
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP.
基因功能參考文獻：
1. insulin-like growth factor 1-induced eIF2B activation in neurons is effected by protein phosphatase 1, the activation of which is mediated by the MEK/MAPK signaling pathway PMID: 12624094
2. The eukaryotic initiation factor 2B beta, gamma, delta and epsilon subunit protein levels are maximal at embryonic day 18 and then decrease during development. Aged hippocampus contain only trace amounts of these subunits. PMID: 12850562
3. Significant increases in the relative abundance of the mRNAs coding for the epsilon (33%) and gamma (26%) subunits of eukaryotic initiation factor (eIF) 2B were observed 48 h after the exercise bout. PMID: 14565967
蛋白家族：

EIF-2B alpha/beta/delta subunits family
數據庫鏈接：

KEGG: rno:117019

UniGene: Rn.11060