Recombinant Rat Tonin (Klk2)

中文名稱：

大鼠Klk2重組蛋白
貨號：

CSB-YP012453RA
規格：
來源：

Yeast
其他：

中文名稱：

大鼠Klk2重組蛋白
貨號：

CSB-EP012453RA-B
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

大鼠Klk2重組蛋白
貨號：

CSB-BP012453RA
規格：
來源：

Baculovirus
其他：

中文名稱：

大鼠Klk2重組蛋白
貨號：

CSB-MP012453RA
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
相關產品
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

Klk2
Uniprot No.：

P00759
別名：

Klk2; Klk-2; Ton; Tonin; EC 3.4.21.35; Esterase 1; Glandular kallikrein-2; rGK-2; RSKG-5; S2 kallikrein
種屬：

Rattus norvegicus (Rat)
蛋白長度：

Full Length of Mature Protein
表達區域：

25-259
氨基酸序列

IVGGYK CEKNSQPWQV AVINEYLCGG VLIDPSWVIT AAHCYSNNYQ VLLGRNNLFK DEPFAQRRLV RQSFRHPDYI PLIVTNDTEQ PVHDHSNDLM LLHLSEPADI TGGVKVIDLP TKEPKVGSTC LASGWGSTNP SEMVVSHDLQ CVNIHLLSNE KCIETYKDNV TDVMLCAGEM EGGKDTCAGD SGGPLICDGV LQGITSGGAT PCAKPKTPAI YAKLIKFTSW IKKVMKENP
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

This protein has both trypsin- and chymotrypsin-like activities, being able to release angiotensin II from angiotensin I or angiotensinogen.
基因功能參考文獻：
1. the environment of tonin abundance may increase N-domain ACE activity liberated by a secretase able to cleave somatic ACE. PMID: 26216430
2. Tonin in the brain may represent an alternative pathway for angiotensin II generation with effects on the cardiovascular system. PMID: 20180641
3. expression in the rat brain and mediation of the central production of angiotensin II PMID: 12044607
4. tonin may play a role in the process of heart hypertrophy PMID: 12543632
5. KLK2 rat gene was expressed at high levels in the submandibular glands of transgenic mice. PMID: 17366701
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蛋白家族：

Peptidase S1 family, Kallikrein subfamily
組織特異性：

Found in submaxillary gland.
數據庫鏈接：

KEGG: rno:24841

STRING: 10116.ENSRNOP00000025701

UniGene: Rn.9882