Recombinant Rat Pro-neuregulin-2, membrane-bound isoform (Nrg2), partial

中文名稱：

大鼠Nrg2重組蛋白
貨號：

CSB-YP016078RA1
規(guī)格：
來源：

Yeast
其他：

中文名稱：

大鼠Nrg2重組蛋白
貨號：

CSB-EP016078RA1
規(guī)格：
來源：

E.coli
其他：

中文名稱：

大鼠Nrg2重組蛋白
貨號：

CSB-EP016078RA1-B
規(guī)格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

大鼠Nrg2重組蛋白
貨號：

CSB-BP016078RA1
規(guī)格：
來源：

Baculovirus
其他：

中文名稱：

大鼠Nrg2重組蛋白
貨號：

CSB-MP016078RA1
規(guī)格：
來源：

Mammalian cell
其他：

產(chǎn)品詳情
產(chǎn)品評價
相關(guān)產(chǎn)品
靶點詳情

產(chǎn)品詳情

純度：

>85% (SDS-PAGE)
基因名：

Nrg2
Uniprot No.：

O35569
別名：

Nrg2; Ntak; Pro-neuregulin-2, membrane-bound isoform; Pro-NRG2
種屬：

Rattus norvegicus (Rat)
蛋白長度：

Partial
蛋白標(biāo)簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產(chǎn)品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復(fù)溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質(zhì)期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產(chǎn)品評價

靶點詳情

功能：

Direct ligand for ERBB3 and ERBB4 tyrosine kinase receptors. Concomitantly recruits ERBB1 and ERBB2 coreceptors, resulting in ligand-stimulated tyrosine phosphorylation and activation of the ERBB receptors. May also promote the heterodimerization with the EGF receptor.
基因功能參考文獻(xiàn)：
1. These results imply that NRG2 may play a critical role in network integration of newborn neurons PMID: 26674872
2. In neuronal primary cultures from developing rat hippocampus, neuregulin 2 (NRG-2) is restricted to neuronal somas and dendrites. PMID: 15048684
3. These results provide a potential role for the previously reported, paradoxical perisynaptic accumulation of Nrg-2alpha, the isoform with the least AChR-inducing activity when presented in a soluble form. PMID: 16944454
亞細(xì)胞定位：

[Pro-neuregulin-2, membrane-bound isoform]: Cell membrane; Single-pass type I membrane protein.; [Neuregulin-2]: Secreted.
蛋白家族：

Neuregulin family
組織特異性：

Expressed in most parts of the brain, especially the olfactory bulb and cerebellum where it localizes in granule and Purkinje cells. In the hippocampus, found in the granule cells of the dentate gyrus. In the basal forebrain, found in the cholinergic cell
數(shù)據(jù)庫鏈接：

KEGG: rno:432361

STRING: 10116.ENSRNOP00000025901

UniGene: Rn.22434