Recombinant Rat Nuclear transcription factor Y subunit gamma (Nfyc)

中文名稱：

大鼠Nfyc重組蛋白
貨號：

CSB-YP730802RA
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

大鼠Nfyc重組蛋白
貨號：

CSB-EP730802RA
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

大鼠Nfyc重組蛋白
貨號：

CSB-EP730802RA-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

大鼠Nfyc重組蛋白
貨號：

CSB-BP730802RA
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

大鼠Nfyc重組蛋白
貨號：

CSB-MP730802RA
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

Nfyc
Uniprot No.：

Q62725
別名：

Nfyc; Nuclear transcription factor Y subunit gamma; CAAT box DNA-binding protein subunit C; CCAAT-binding transcription factor subunit C; CBF-C; Nuclear transcription factor Y subunit C; NF-YC
種屬：

Rattus norvegicus (Rat)
蛋白長度：

full length protein
表達區域：

1-335
氨基酸序列

MSTEGGFGST SSSDAQQSLQ SFWPRVMEEI RNLTVKDFRV QELPLARIKK IMKLDEDVKM ISAEAPVLFA KAAQIFITEL TLRAWIHTED NKRRTLQRND IAMAITKFDQ FDFLIDIVPR DELKPPKRQE EVRQSVTPAE PVQYYFTLAQ QPTAVQVQGQ QQGQQTTSST TTIQPGQIII AQPQQGQTTP VTMQVGEGQQ VQIVQAQPQG QAQQAQSGTG QTMQVMQQII TNTGEIQQIP VQLNAGQLQY IRLAQPVSGT QVVQGQIQTL ATNAQQITQT EVQQGQQQFS QFTDGQQLYQ IQQVTMPAGQ DLAQPMFIQS ANQPSDGQTP QVTGD
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Component of the sequence-specific heterotrimeric transcription factor (NF-Y) which specifically recognizes a 5'-CCAAT-3' box motif found in the promoters of its target genes. NF-Y can function as both an activator and a repressor, depending on its interacting cofactors.
基因功能參考文獻：
1. Upregulation of NF-YC might play an important role in the pathophysiology via proapoptotic protein Bim after middle cerebral artery occlusion. PMID: 24014123
2. NF-Y cooperates with FOXO3a to recruit CBP/p300 to the bim promoter to form a stable multi-protein/DNA complex that activates bim transcription after survival factor withdrawal. PMID: 21164521
3. NF-Y binds to p73 and transcriptionally regulates platelet derived growth factor beta receptor PMID: 12167641
4. polyunsaturated fatty acids decrease in vivo binding of NF-Y and SREBP-1c to the proximal promoter of the hepatic fatty acid synthase gene PMID: 17313375
亞細胞定位：

Nucleus.
蛋白家族：

NFYC/HAP5 subunit family
數據庫鏈接：

KEGG: rno:25337

STRING: 10116.ENSRNOP00000053489

UniGene: Rn.1457