Recombinant Rat Myosin phosphatase Rho-interacting protein (Mprip), partial

中文名稱：

大鼠Mprip重組蛋白
貨號：

CSB-YP863659RA
規格：
來源：

Yeast
其他：

中文名稱：

大鼠Mprip重組蛋白
貨號：

CSB-EP863659RA
規格：
來源：

E.coli
其他：

中文名稱：

大鼠Mprip重組蛋白
貨號：

CSB-EP863659RA-B
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

大鼠Mprip重組蛋白
貨號：

CSB-BP863659RA
規格：
來源：

Baculovirus
其他：

中文名稱：

大鼠Mprip重組蛋白
貨號：

CSB-MP863659RA
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

Mprip
Uniprot No.：

Q9ERE6
別名：

Mprip; Mrip; Rhoip3; Myosin phosphatase Rho-interacting protein; Rho-interacting protein 3; RIP3; p116Rip
種屬：

Rattus norvegicus (Rat)
蛋白長度：

Partial
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Targets myosin phosphatase to the actin cytoskeleton. Required for the regulation of the actin cytoskeleton by RhoA and ROCK1. Depletion leads to an increased number of stress fibers in smooth muscle cells through stabilization of actin fibers by phosphorylated myosin. Overexpression of MRIP as well as its F-actin-binding region leads to disassembly of stress fibers in neuronal cells.
基因功能參考文獻：
1. The results indicated that RIP3 is expressed differentially in retinal neurons in adult rats, including subsets of ganglion cells, amacrine and horizontal cells. RIP3 protein levels are elevated rapidly following aHIOP PMID: 23374330
2. decreased insulin-stimulated MRIP/MYPT1 association may contribute to the impaired insulin-mediated vasodilation observed in the diabetic vasculature PMID: 22322972
3. myosin phosphatase-rho interacting protein is a scaffold linking RhoA to regulate myosin phosphatase at the stress fiber. PMID: 17661354
亞細胞定位：

Cytoplasm, cytoskeleton.
數據庫鏈接：

KEGG: rno:116504

STRING: 10116.ENSRNOP00000045501

UniGene: Rn.2641