Recombinant Rat Mothers against decapentaplegic homolog 9 (Smad9)

中文名稱：

大鼠Smad9重組蛋白
貨號：

CSB-YP021794RA
規格：
來源：

Yeast
其他：

中文名稱：

大鼠Smad9重組蛋白
貨號：

CSB-EP021794RA
規格：
來源：

E.coli
其他：

中文名稱：

大鼠Smad9重組蛋白
貨號：

CSB-EP021794RA-B
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

大鼠Smad9重組蛋白
貨號：

CSB-BP021794RA
規格：
來源：

Baculovirus
其他：

中文名稱：

大鼠Smad9重組蛋白
貨號：

CSB-MP021794RA
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

Smad9
Uniprot No.：

O54835
別名：

Smad9; Madh8; Madh9; Smad8; Mothers against decapentaplegic homolog 9; MAD homolog 9; Mothers against DPP homolog 9; SMAD family member 9; SMAD 9; Smad9; Smad8
種屬：

Rattus norvegicus (Rat)
蛋白長度：

Full length protein
表達區域：

1-434
氨基酸序列

MHPSTPISSL FSFTSPAVKR LLGWKQGDEE EKWAEKAVDS LVKKLKKKKG AMDELERALS CPGQPSKCVT IPRSLDGRLQ VSHRKGLPHV IYCRVWRWPD LQSHHELKPL ECCEFPFGSK QKEVCINPYH YRRVETPVLP PVLVPRHSEY NPQLSLLAKF RSASLHSEPL MPHNATYPDS FQQSLGPAPP SSPGHVFPQS PCPTSYPQSP GSPSESDSPY QHSDFRPVCY EEPLHWCSVA YYELNNRVGE TFQASSRSVL IDGFTDPSNN RNRFCLGLLS NVNRNSTIEN TRRHIGKGVH LYYVGGEVYA ECVSDSSIFV QSRNCNYQHG FHPATVCKIP SGCSLKVFNN QLFAQLLAQL LAQSVHHGFE VVYELTKMCT IRMSFVKGWG AEYHRQDVTS TPCWIEIHLH GPLQWLDKVL TQMGSPHNPI SSVS
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD9 is a receptor-regulated SMAD (R-SMAD). Has been shown to be activated by activin type I receptor-like kinase-2 (ALK-2) which stimulates heteromerization between SMAD9 and SMAD4. ALK-2 binds TGF-beta, activin and BMP.
基因功能參考文獻：
1. Data suggest that Mullerian inhibiting substance (MIS) initiates an epithelial-to-mesenchymal transition of MIS receptor-expressing cells and specifies the components of the receptor/SMAD8 signaling pathway by regulating their expression. PMID: 16687449
2. Expression of BMP receptors Ib and II, and Smad 8 was downregulated in lungs but not kidneys of MCT-treated rats. PMID: 17347486
亞細胞定位：

Cytoplasm. Nucleus.
蛋白家族：

Dwarfin/SMAD family
數據庫鏈接：

KEGG: rno:85435

STRING: 10116.ENSRNOP00000000102

UniGene: Rn.10862