Recombinant Rat Kinesin light chain 1 (Klc1)

中文名稱：

大鼠Klc1重組蛋白
貨號：

CSB-YP012379RA
說明書：

MSDS Datasheet
規(guī)格：
來源：

Yeast
其他：

中文名稱：

大鼠Klc1重組蛋白
貨號：

CSB-EP012379RA
說明書：

MSDS Datasheet
規(guī)格：
來源：

E.coli
其他：

中文名稱：

大鼠Klc1重組蛋白
貨號：

CSB-EP012379RA-B
說明書：

MSDS Datasheet
規(guī)格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

大鼠Klc1重組蛋白
貨號：

CSB-BP012379RA
說明書：

MSDS Datasheet
規(guī)格：
來源：

Baculovirus
其他：

中文名稱：

大鼠Klc1重組蛋白
貨號：

CSB-MP012379RA
說明書：

MSDS Datasheet
規(guī)格：
來源：

Mammalian cell
其他：

產(chǎn)品詳情
產(chǎn)品評價
靶點詳情

產(chǎn)品詳情

純度：

>85% (SDS-PAGE)
基因名：

Klc1
Uniprot No.：

P37285
別名：

Klc1; Klc; Kns2Kinesin light chain 1; KLC 1
種屬：

Rattus norvegicus (Rat)
蛋白長度：

Full length protein
表達區(qū)域：

1-560
氨基酸序列

MHDNMSTMVY MKEEKLEKLT QDEIISKTKQ VIQGLEALKN EHNSILQSLL ETLKCLKKDD ESNLVEEKSS MIRKSLEMLE LGLSEAQVMM ALSNHLNAVE SEKQKLRAQV RRLCQENQWL RDELANTQQK LQKSEQSVAQ LEEEKKHLEF MNQLKKYDDD ISPSEDKDSD SSKEPLDDLF PNDEDDPGQG IQQQHSSAAA AAQQGGYEIP ARLRTLHNLV IQYASQGRYE VAVPLCKQAL EDLEKTSGHD HPDVATMLNI LALVYRDQNK YKDAANLLND ALAIREKTLG RDHPAVAATL NNLAVLYGKR GKYKEAEPLC KRALEIREKV LGKDHPDVAK QLNNLALLCQ NQGKYEEVEY YYQRALEIYQ TKLGPDDPNV AKTKNNLASC YLKQGKFKQA ETLYKEILTR AHEREFGSVD DENKPIWMHA EEREECKGKQ KDGSSFGEYG GWYKACKVDS PTVTTTLKNL GALYRRQGKF EAAETLEEAA LRSRKQGLDN VHKQRVAEVL NDPENVEKRR SRESLNVDVV KYESGPDGGE EVSMSVEWNG MRKMKLGLVK
蛋白標(biāo)簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產(chǎn)品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復(fù)溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質(zhì)期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產(chǎn)品評價

靶點詳情

功能：

Kinesin is a microtubule-associated force-producing protein that may play a role in organelle transport. The light chain may function in coupling of cargo to the heavy chain or in the modulation of its ATPase activity.
基因功能參考文獻：
1. wild-type torsinA undergoes anterograde transport along microtubules mediated by kinesin and may act as a molecular chaperone regulating kinesin activity and/or cargo binding PMID: 14970196
2. Calsyntenin-1 links a certain type of vesicular and tubulovesicular organelles to the Kinesin-1 motor. PMID: 16760430
3. We observed that acetyl-l-carnitine increases the light-chain subunit of kinesin-1 gene expression.The fast anterograde axonal transport of amyloid-beta peptide is mediated by direct binding to the light-chain subunit of kinesin-1. PMID: 18761385
亞細胞定位：

Cell projection, growth cone. Cytoplasmic vesicle. Cytoplasm, cytoskeleton.
蛋白家族：

Kinesin light chain family
組織特異性：

Expressed in brain (at protein level).
數(shù)據(jù)庫鏈接：

KEGG: rno:171041

STRING: 10116.ENSRNOP00000015935

UniGene: Rn.106230