Recombinant Rat Hyaluronan and proteoglycan link protein 1 (Hapln1)

中文名稱：

大鼠Hapln1重組蛋白
貨號：

CSB-YP010130RA
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

大鼠Hapln1重組蛋白
貨號：

CSB-EP010130RA
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

大鼠Hapln1重組蛋白
貨號：

CSB-EP010130RA-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

大鼠Hapln1重組蛋白
貨號：

CSB-BP010130RA
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

大鼠Hapln1重組蛋白
貨號：

CSB-MP010130RA
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

Hapln1
Uniprot No.：

P03994
別名：

Hapln1; Crtl1; Hyaluronan and proteoglycan link protein 1; Cartilage-linking protein 1; Cartilage-link protein; Proteoglycan link protein
種屬：

Rattus norvegicus (Rat)
蛋白長度：

Full Length of Mature Protein
表達區域：

10-354
氨基酸序列

I SVCRADHLSD SYTPDQDRVI HIQAENGPRL LVEAEQAKVF SHRGGNVTLP CKFYRDPTAF GSGIHKIRIK WTKLTSDYLR EVDVFVSMGY HKKTYGGYQG RVFLKGGSDN DASLIITDLT LEDYGRYKCE VIEGLEDDTA VVALELQGVV FPYFPRLGRY NLNFHEARQA CLDQDAVIAS FDQLYDAWRG GLDWCNAGWL SDGSVQYPIT KPREPCGGQN TVPGVRNYGF WDKDKSRYDV FCFTSNFNGR FYYLIHPTKL TYDEAVQACL NDGAQIAKVG QIFAAWKLLG YDRCDAGWLA DGSVRYPISR PRRRCSPTEA AVRFVGFPDK KHKLYGVYCF RAYN
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Stabilizes the aggregates of proteoglycan monomers with hyaluronic acid in the extracellular cartilage matrix.
基因功能參考文獻：
1. our findings demonstrate that the formation of perineuronal nets triggered by neuronal Crtl1 synthesis is a key event in the diminuation of plasticity in the adult CNS PMID: 20566484
2. HAPLN1 may promote periovulatory granulosa cell survival, which would facilitate their differentiation into luteal cells. PMID: 20339004
3. study represents the first report that follicle stimulating hormone amplifies insulin-like growth factor-I-mediated cartilage link protein Crtl1 production, possibly via phosphatidylinositol 3-kinase-Akt signaling cascades in rat granulosa cells PMID: 12586755
4. Aggrecan, hyaluronan synthases, and, particularly, link protein 1 might be crucial elements for the initial assembly of perineuronal nets. PMID: 17206619
亞細胞定位：

Secreted, extracellular space, extracellular matrix.
蛋白家族：

HAPLN family
數據庫鏈接：

UniGene: Rn.50531