Recombinant Rat ERC protein 2 (Erc2), partial

中文名稱：

大鼠Erc2重組蛋白
貨號：

CSB-YP811706RA
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

大鼠Erc2重組蛋白
貨號：

CSB-EP811706RA
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

大鼠Erc2重組蛋白
貨號：

CSB-EP811706RA-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

大鼠Erc2重組蛋白
貨號：

CSB-BP811706RA
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

大鼠Erc2重組蛋白
貨號：

CSB-MP811706RA
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

Erc2
Uniprot No.：

Q8K3M6
別名：

Erc2; Cast1; CmbpERC protein 2; CAZ-associated structural protein 1; CAST1; Cast; Cytomatrix protein p110
種屬：

Rattus norvegicus (Rat)
蛋白長度：

Partial
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Thought to be involved in the organization of the cytomatrix at the nerve terminals active zone (CAZ) which regulates neurotransmitter release. Seems to act together with BSN. May recruit liprin-alpha proteins to the CAZ.
基因功能參考文獻：
1. characterized a family of active zone proteins whose binding to RIMs, presynaptic active zone proteins that regulate neurotransmitter release, is regulated by tissue-specific alternative splicing PMID: 12391317
2. The interaction between ERC2 and liprin-alpha may be involved in the presynaptic localization of liprin-alpha and the molecular organization of presynaptic active zones. PMID: 12923177
3. RIM1- or Bassoon-binding region of CAST impairs synaptic transmission in cultured superior cervical ganglion neurons PMID: 14734538
4. ERC2 promotes presynaptic syntenin-1 clustering by two distinct mechanisms PMID: 16421316
亞細胞定位：

Cytoplasm. Cell junction, synapse. Cell junction, synapse, presynaptic active zone. Cytoplasm, cytoskeleton. Note=Localized to the active zone of presynaptic density. Colocalizes with RIMS1 and BSN in early stages of synapse formation.
組織特異性：

Predominantly expressed in brain, including hippocampus, cortex, cerebellum, amygdala and olfactory bulb.
數據庫鏈接：

KEGG: rno:259269

STRING: 10116.ENSRNOP00000041403

UniGene: Rn.213719