Recombinant Rat Contactin-1 (Cntn1), partial

中文名稱：

Recombinant Rat Contactin-1(Cntn1) ,partial
貨號：

CSB-YP717360RA
規格：
來源：

Yeast
其他：

中文名稱：

Recombinant Rat Contactin-1(Cntn1) ,partial
貨號：

CSB-EP717360RA
規格：
來源：

E.coli
其他：

中文名稱：

Recombinant Rat Contactin-1(Cntn1) ,partial
貨號：

CSB-EP717360RA-B
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

Recombinant Rat Contactin-1(Cntn1) ,partial
貨號：

CSB-BP717360RA
規格：
來源：

Baculovirus
其他：

中文名稱：

Recombinant Rat Contactin-1(Cntn1) ,partial
貨號：

CSB-MP717360RA
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

Cntn1
Uniprot No.：

Q63198
別名：

Cntn1Contactin-1; Neural cell surface protein F3
種屬：

Rattus norvegicus (Rat)
蛋白長度：

Partial
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Contactins mediate cell surface interactions during nervous system development. Involved in the formation of paranodal axo-glial junctions in myelinated peripheral nerves and in the signaling between axons and myelinating glial cells via its association with CNTNAP1. Participates in oligodendrocytes generation by acting as a ligand of NOTCH1. Its association with NOTCH1 promotes NOTCH1 activation through the released notch intracellular domain (NICD) and subsequent translocation to the nucleus. Interaction with TNR induces a repulsion of neurons and an inhibition of neurite outgrowth.
基因功能參考文獻：
1. Expression of alternatively spliced FnIII domains of tenascin-C is differentially regulated after brain injury, with strong increases of domains B and D that may well influence axonal regeneration and repair processes in the damaged nervous system. PMID: 20451518
2. Data show that the rat F3/contactin gene differs from the mouse gene in that it contains two additional untranslated exons that are alternatively spliced and lacks the homologue mouse untranslated exon 0. PMID: 15967539
亞細胞定位：

Cell membrane; Lipid-anchor, GPI-anchor.
蛋白家族：

Immunoglobulin superfamily, Contactin family
組織特異性：

Expressed by neurons, oligodendrocytes and their progenitors (at protein level). Myelination regulates the expression being downregulated when neurons are in contact with Schwann cells.
數據庫鏈接：

KEGG: rno:117258

STRING: 10116.ENSRNOP00000006219

UniGene: Rn.143291