Recombinant Rat C-C chemokine receptor type 3 (Ccr3), partial

中文名稱：

Recombinant Rat C-C chemokine receptor type 3(Ccr3),partial
貨號：

CSB-YP004842RA1
規格：
來源：

Yeast
其他：

中文名稱：

Recombinant Rat C-C chemokine receptor type 3(Ccr3),partial
貨號：

CSB-EP004842RA1
規格：
來源：

E.coli
其他：

中文名稱：

Recombinant Rat C-C chemokine receptor type 3(Ccr3),partial
貨號：

CSB-EP004842RA1-B
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

Recombinant Rat C-C chemokine receptor type 3(Ccr3),partial
貨號：

CSB-BP004842RA1
規格：
來源：

Baculovirus
其他：

中文名稱：

Recombinant Rat C-C chemokine receptor type 3(Ccr3),partial
貨號：

CSB-MP004842RA1
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
相關產品
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

Ccr3
Uniprot No.：

O54814
別名：

Ccr3; Cmkbr3; C-C chemokine receptor type 3; C-C CKR-3; CC-CKR-3; CCR-3; CCR3; CKR3; CD antigen CD193
種屬：

Rattus norvegicus (Rat)
蛋白長度：

Partial
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Receptor for C-C type chemokine. Binds and responds to a variety of chemokines, including CCL11, CCL26, CCL7, CCL13, RANTES(CCL5) and CCL15. Subsequently transduces a signal by increasing the intracellular calcium ions level. In addition acts as a possible functional receptor for NARS1.
基因功能參考文獻：
1. CCR3 plays no role in choroidal neovascularization development. PMID: 22183343
2. Allergen-induced recruitment of eosinophils in the distal septum and turbinates was maximal at 8h post-challenge, and was correlated with 2-4-fold increase in CCR3 and betac mRNA PMID: 20696593
3. demonstrated that CCR3 is absent from the testes PMID: 11994538
4. Down-regulation of constitutively expressed surface CCR3 levels by interleukin 1-beta in an insulin-producing model system implies receptor internalization for re-utilization or destruction, secretion or both. PMID: 12004163
亞細胞定位：

Cell membrane; Multi-pass membrane protein.
蛋白家族：

G-protein coupled receptor 1 family
組織特異性：

Expressed in spleen but not in astrocytes or microglia.
數據庫鏈接：

KEGG: rno:117027

STRING: 10116.ENSRNOP00000008809

UniGene: Rn.9890