Recombinant Rat Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2 (Agap2), partial

中文名稱：

Recombinant Rat Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2(Agap2) ,partial
貨號：

CSB-YP805588RA
規(guī)格：
來源：

Yeast
其他：

中文名稱：

Recombinant Rat Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2(Agap2) ,partial
貨號：

CSB-EP805588RA
規(guī)格：
來源：

E.coli
其他：

中文名稱：

Recombinant Rat Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2(Agap2) ,partial
貨號：

CSB-EP805588RA-B
規(guī)格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

Recombinant Rat Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2(Agap2) ,partial
貨號：

CSB-BP805588RA
規(guī)格：
來源：

Baculovirus
其他：

中文名稱：

Recombinant Rat Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2(Agap2) ,partial
貨號：

CSB-MP805588RA
規(guī)格：
來源：

Mammalian cell
其他：

產(chǎn)品詳情
產(chǎn)品評價
靶點詳情

產(chǎn)品詳情

純度：

>85% (SDS-PAGE)
基因名：

Agap2
Uniprot No.：

Q8CGU4
別名：

Agap2; Centg1Arf-GAP with GTPase; ANK repeat and PH domain-containing protein 2; AGAP-2; Centaurin-gamma-1; Cnt-g1; Phosphatidylinositol 3-kinase enhancer; PIKE
種屬：

Rattus norvegicus (Rat)
蛋白長度：

Partial
蛋白標(biāo)簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產(chǎn)品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復(fù)溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質(zhì)期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產(chǎn)品評價

靶點詳情

功能：

GTPase-activating protein (GAP) for ARF1 and ARF5, which also shows strong GTPase activity. Participates in the prevention of neuronal apoptosis by enhancing PI3 kinase activity. Aids the coupling of metabotropic glutamate receptor 1 (GRM1) to cytoplasmic PI3 kinase by interacting with Homer scaffolding proteins, and also seems to mediate anti-apoptotic effects of NGF by activating nuclear PI3 kinase.
基因功能參考文獻(xiàn)：
1. PIKE plays pivotal roles to advance oligodendroglia development and myelinogenesis through Akt/mTOR activation. PMID: 24449917
2. PIKE is a critical factor in controlling synaptic AMPA receptor insertion. PMID: 21847098
3. Pike/nuclear PI 3-kinase signaling mediates the antiapoptotic actions of nerve growth factor in the cell nucleus. PMID: 15385964
亞細(xì)胞定位：

Cytoplasm. Nucleus.
蛋白家族：

Centaurin gamma-like family
組織特異性：

Present in cortex, hippocampus and olfactory bulb but absent in cerebellum (at protein level).
數(shù)據(jù)庫鏈接：

KEGG: rno:65218

STRING: 10116.ENSRNOP00000029533

UniGene: Rn.91094