Recombinant Rabbit Phosphatidylcholine-sterol acyltransferase (LCAT)

中文名稱：

小圓錐花果LCAT重組蛋白
貨號：

CSB-YP012783RB
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

小圓錐花果LCAT重組蛋白
貨號：

CSB-EP012783RB
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

小圓錐花果LCAT重組蛋白
貨號：

CSB-EP012783RB-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

小圓錐花果LCAT重組蛋白
貨號：

CSB-BP012783RB
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

小圓錐花果LCAT重組蛋白
貨號：

CSB-MP012783RB
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

LCAT
Uniprot No.：

P53761
別名：

LCATPhosphatidylcholine-sterol acyltransferase; EC 2.3.1.43; Lecithin-cholesterol acyltransferase; Phospholipid-cholesterol acyltransferase
種屬：

Oryctolagus cuniculus (Rabbit)
蛋白長度：

Full Length of Mature Protein
表達區域：

25-440
氨基酸序列

FWLLNV LFPPHTTPKA ELSNHTRPVI LVPGCLGNQL EAKLDKPSVV NWMCYRKTED FFTIWLDLNM FLPLGVDCWI DNTRVVYNRS SGRVVISPGV QIRVPGFGKT YSVEYLDNNK LAGYMHTLVQ NLVNNGYVRD ETVRAAPYDW RLEPSQQEEY YGKLAGLVEE MHAAYGKPVF LIGHSLGCLH LLYFLLRQPQ SWKDRFIDGF ISLGAPWGGS IKPMLVLASG DNQGIPLMSS IKLREEQRIT TTSPWMFPSQ GVWPEDHVFI STPSFNYTGR DFKRFFEDLH FEEGWYMWLQ SRDLLAGLPA PGVEVYCLYG IGLPTPHTYI YDHGFPYTDP VGVLYEDGDD TVATSSTDLC GLWRGRQPQP VHLLPLHETE HLNMVFSNQT LEHINAILLG AYRSGTPASP TASPGSPPPE
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Central enzyme in the extracellular metabolism of plasma lipoproteins. Synthesized mainly in the liver and secreted into plasma where it converts cholesterol and phosphatidylcholines (lecithins) to cholesteryl esters and lysophosphatidylcholines on the surface of high and low density lipoproteins (HDLs and LDLs). The cholesterol ester is then transported back to the liver. Also produced in the brain by primary astrocytes, and esterifies free cholesterol on nascent APOE-containing lipoproteins secreted from glia and influences cerebral spinal fluid (CSF) APOE- and APOA1 levels. Together with APOE and the cholesterol transporter ABCA1, plays a key role in the maturation of glial-derived, nascent lipoproteins. Required for remodeling high-density lipoprotein particles into their spherical forms. Has a preference for plasma 16:0-18:2 or 18:O-18:2 phosphatidylcholines. Catalyzes the hydrolysis of 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine (platelet-activating factor or PAF) to 1-O-alkyl-sn-glycero-3-phosphocholine (lyso-PAF). Also catalyzes the transfer of the acetate group from PAF to 1-hexadecanoyl-sn-glycero-3-phosphocholine forming lyso-PAF. Catalyzes the esterification of (24S)-hydroxycholesterol (24(S)OH-C), also known as cerebrosterol to produce 24(S)OH-C monoesters.
基因功能參考文獻：
1. LCAT cholesterol esterification is associated with the increase of ApoE/ApoA-I ratio during atherosclerosis progression in rabbit. PMID: 22562159
亞細胞定位：

Secreted.
蛋白家族：

AB hydrolase superfamily, Lipase family
組織特異性：

Detected in blood plasma (at protein level). Highly expressed in liver.
數據庫鏈接：

KEGG: ocu:100008978

STRING: 9986.ENSOCUP00000018119

UniGene: Ocu.2553