Recombinant Probable endonuclease III homolog (nth-1)

中文名稱：

秀麗隱桿線蟲nth-1重組蛋白
貨號：

CSB-YP347471CXY
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

秀麗隱桿線蟲nth-1重組蛋白
貨號：

CSB-EP347471CXY
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

秀麗隱桿線蟲nth-1重組蛋白
貨號：

CSB-EP347471CXY-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

秀麗隱桿線蟲nth-1重組蛋白
貨號：

CSB-BP347471CXY
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

秀麗隱桿線蟲nth-1重組蛋白
貨號：

CSB-MP347471CXY
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

nth-1
Uniprot No.：

P54137
別名：

nth-1; R10E4.5; Endonuclease III homolog; CeNTH; EC 3.2.2.-; EC 4.2.99.18; Bifunctional DNA N-glycosylase/DNA-(apurinic or apyrimidinic site) lyase; DNA glycosylase/AP lyase
種屬：

Caenorhabditis elegans
蛋白長度：

full length protein
表達區域：

1-298
氨基酸序列

MHSFSMKRVV ASSSVAAVAT CDVEGTVVAW RRDVELIRKM RKDMIAPVDT MGCHKLADPL AAPPVHRFQV LVALMLSSQT RDEVNAAAMK RLKDHGLSIG KILEFKVPDL ETILCPVGFY KRKAVYLQKT AKILKDDFSG DIPDSLDGLC ALPGVGPKMA NLVMQIAWGE CVGIAVDTHV HRISNRLGWI KTSTPEKTQK ALEILLPKSE WQPINHLLVG FGQMQCQPVR PKCGTCLCRF TCPSSTAKNV KSETEETSTS IEVKQEVEDE FEDEKPAKKI KKTRKTRTKI EVKTESET
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines.
基因功能參考文獻：
1. we could detect no deficiency in base excision repair in the nth-1 strain. PMID: 22959841
2. Data show that the protein encoded by the sequence containing both R10E4.5 and the 117-bp region upstream from it, and found that the protein had the NTH activity. PMID: 19481506
亞細胞定位：

Nucleus. Mitochondrion.
蛋白家族：

Nth/MutY family
數據庫鏈接：

KEGG: cel:CELE_R10E4.5

STRING: 6239.R10E4.5d

UniGene: Cel.10201