Recombinant Pig Insulin-like 3 (INSL3)

中文名稱：

野豬INSL3重組蛋白
貨號：

CSB-YP011747PI
說明書：

MSDS Datasheet
規(guī)格：
來源：

Yeast
其他：

中文名稱：

野豬INSL3重組蛋白
貨號：

CSB-EP011747PI
說明書：

MSDS Datasheet
規(guī)格：
來源：

E.coli
其他：

中文名稱：

野豬INSL3重組蛋白
貨號：

CSB-EP011747PI-B
說明書：

MSDS Datasheet
規(guī)格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

野豬INSL3重組蛋白
貨號：

CSB-BP011747PI
說明書：

MSDS Datasheet
規(guī)格：
來源：

Baculovirus
其他：

中文名稱：

野豬INSL3重組蛋白
貨號：

CSB-MP011747PI
說明書：

MSDS Datasheet
規(guī)格：
來源：

Mammalian cell
其他：

產(chǎn)品詳情
產(chǎn)品評價
靶點詳情

產(chǎn)品詳情

純度：

>85% (SDS-PAGE)
基因名：

INSL3
Uniprot No.：

P51461
別名：

INSL3; RLFInsulin-like 3; Leydig insulin-like peptide; Ley-I-L; Relaxin-like factor) [Cleaved into: Insulin-like 3 B chain; Insulin-like 3 A chain]
種屬：

Sus scrofa (Pig)
蛋白長度：

Cytoplasmic domain
表達區(qū)域：

27-56
氨基酸序列

QEAP EKLCGHHFVR ALVRLCGGPR WSPEDG
蛋白標(biāo)簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產(chǎn)品提供形式：

Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復(fù)溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質(zhì)期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產(chǎn)品評價

靶點詳情

功能：

Seems to play a role in testicular function. May be a trophic hormone with a role in testicular descent in fetal life. Is a ligand for LGR8 receptor.
基因功能參考文獻：
1. This study thus provides evidence for substantial transfer of INSL3 between fetuses, and probably also across the placenta, emphasizing the vulnerability of the fetus to extrinsic hormonal influences within the uterus. PMID: 27031644
2. RXFP2 was expressed in boar meiotic and post-meiotic germ cells, where INSL3 neutralization led to increased germ cell apoptosis and reduced sperm output, suggesting that INSL3 acts as a survival/anti-apoptotic factor in maintaining sperm production. PMID: 25562614
3. The study suggests the existence of RLF/INSL3-RXFP2 signaling in germ cells of boars. PMID: 24640564
4. Circulating INSL3 was shown to increase progressively during development PMID: 24464024
5. These results indicate that boar RLF/INSL3 is secreted from testicular Leydig cells as a B-C-A monomeric structure with full biological activity. PMID: 21899516
6. insl3 gene SNPs can be excluded as a common genetic basis for hernia inguinalis in pigs PMID: 15068335
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亞細胞定位：

Secreted.
蛋白家族：

Insulin family
組織特異性：

Expressed exclusively in prenatal and postnatal Leydig cells.
數(shù)據(jù)庫鏈接：

KEGG: ssc:397024

STRING: 9823.ENSSSCP00000014767

UniGene: Ssc.11990