Recombinant Pig Apolipoprotein E (APOE)

中文名稱：

Recombinant Pig Apolipoprotein E(APOE)
貨號：

CSB-YP001936PI
規格：
來源：

Yeast
其他：

中文名稱：

Recombinant Pig Apolipoprotein E(APOE)
貨號：

CSB-EP001936PI
規格：
來源：

E.coli
其他：

中文名稱：

Recombinant Pig Apolipoprotein E(APOE)
貨號：

CSB-EP001936PI-B
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

Recombinant Pig Apolipoprotein E(APOE)
貨號：

CSB-BP001936PI
規格：
來源：

Baculovirus
其他：

中文名稱：

Recombinant Pig Apolipoprotein E(APOE)
貨號：

CSB-MP001936PI
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
相關產品
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

APOE
Uniprot No.：

P18650
別名：

APOEApolipoprotein E; Apo-E
種屬：

Sus scrofa (Pig)
蛋白長度：

Full Length of Mature Protein
表達區域：

19-317
氨基酸序列

ED EPGPPPEVHV WWEESKWQGS QPWEQALGRF WDYLRWVQSL SDQVQEELLS TKVTQELTEL IEESMKEVKA YREELEAQLG PVTQETQARL SKELQAAQAR VGADMEDVRN RLVLYRSEVH NMLGQTTEEL RSRLASHLRN VRKRLVRDTE DLQKRLAVYQ AGLREGAERS VSALRERLGP LVEQGRLRAA TLSTRAGQPL RERAEAWGQK LRGRLEEMGS RTRDRLDEMR DELEEVRTKV EEQGSQLRLQ AEAFQARLKG WFEPLVEDMR RQWAGLVERM QSAVSISSST SAPSDNQ
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apoliproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma. As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density lipoproteins (IDL) but shows a preferential binding to high-density lipoproteins (HDL). It also binds a wide range of cellular receptors including the LDL receptor/LDLR and the very low-density lipoprotein receptor/VLDLR that mediate the cellular uptake of the APOE-containing lipoprotein particles. Finally, APOE has also a heparin-binding activity and binds heparan-sulfate proteoglycans on the surface of cells, a property that supports the capture and the receptor-mediated uptake of APOE-containing lipoproteins by cells.
基因功能參考文獻：
1. These data suggest that the -155T>A mutation in the promoter region of the porcine APOE gene is an important functional variant PMID: 21549015
亞細胞定位：

Secreted. Secreted, extracellular space. Secreted, extracellular space, extracellular matrix.
蛋白家族：

Apolipoprotein A1/A4/E family
數據庫鏈接：

KEGG: ssc:397576

STRING: 9823.ENSSSCP00000003343

UniGene: Ssc.1342