Recombinant Oncorhynchus kisutch Insulin-like growth factor I (igf1)

中文名稱：

Recombinant Oncorhynchus kisutch Insulin-like growth factor I(igf1)
貨號：

CSB-YP324597OBH
規格：
來源：

Yeast
其他：

中文名稱：

Recombinant Oncorhynchus kisutch Insulin-like growth factor I(igf1)
貨號：

CSB-EP324597OBH
規格：
來源：

E.coli
其他：

中文名稱：

Recombinant Oncorhynchus kisutch Insulin-like growth factor I(igf1)
貨號：

CSB-EP324597OBH-B
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

Recombinant Oncorhynchus kisutch Insulin-like growth factor I(igf1)
貨號：

CSB-BP324597OBH
規格：
來源：

Baculovirus
其他：

中文名稱：

Recombinant Oncorhynchus kisutch Insulin-like growth factor I(igf1)
貨號：

CSB-MP324597OBH
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

igf1
Uniprot No.：

P17085
別名：

igf1Insulin-like growth factor I; IGF-I; Somatomedin
種屬：

Oncorhynchus kisutch (Coho salmon)
蛋白長度：

Full Length of Mature Protein
表達區域：

45-114
氨基酸序列

GPETLC GAELVDTLQF VCGERGFYFS KPTGYGPSSR RSHNRGIVDE CCFQSCELRR LEMYCAPVKS GKAA
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. Acts as a ligand for IGF1R. Binds to the alpha subunit of IGF1R, leading to the activation of the intrinsic tyrosine kinase activity which autophosphorylates tyrosine residues in the beta subunit thus initiatiating a cascade of down-stream signaling events leading to activation of the PI3K-AKT/PKB and the Ras-MAPK pathways. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integrins and IGFR1 are essential for IGF1 signaling.
亞細胞定位：

Secreted.
蛋白家族：

Insulin family
組織特異性：

All the isoforms are expressed in embryos, juvenile and adult liver, muscle and brain. At least one isoform is expressed in heart, kidney, testes, ovary, adipose tissue and spleen of juvenile salmon.
數據庫鏈接：

UniGene: Ssa.40