Recombinant Mouse Zinc finger MIZ domain-containing protein 1 (Zmiz1), partial

中文名稱：

小鼠Zmiz1重組蛋白
貨號(hào)：

CSB-YP744029MO
說明書：

MSDS Datasheet
規(guī)格：
來源：

Yeast
其他：

中文名稱：

小鼠Zmiz1重組蛋白
貨號(hào)：

CSB-EP744029MO
說明書：

MSDS Datasheet
規(guī)格：
來源：

E.coli
其他：

中文名稱：

小鼠Zmiz1重組蛋白
貨號(hào)：

CSB-EP744029MO-B
說明書：

MSDS Datasheet
規(guī)格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

小鼠Zmiz1重組蛋白
貨號(hào)：

CSB-BP744029MO
說明書：

MSDS Datasheet
規(guī)格：
來源：

Baculovirus
其他：

中文名稱：

小鼠Zmiz1重組蛋白
貨號(hào)：

CSB-MP744029MO
說明書：

MSDS Datasheet
規(guī)格：
來源：

Mammalian cell
其他：

產(chǎn)品詳情
產(chǎn)品評(píng)價(jià)
靶點(diǎn)詳情

產(chǎn)品詳情

純度：

>85% (SDS-PAGE)
基因名：

Zmiz1
Uniprot No.：

Q6P1E1
別名：

Zmiz1; Rai17; Zimp10; Zinc finger MIZ domain-containing protein 1; PIAS-like protein Zimp10; Retinoic acid-induced protein 17
種屬：

Mus musculus (Mouse)
蛋白長(zhǎng)度：

Partial
蛋白標(biāo)簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產(chǎn)品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復(fù)溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲(chǔ)存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質(zhì)期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項(xiàng)：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

功能：

Acts as transcriptional coactivator. Increases ligand-dependent transcriptional activity of AR and promotes AR sumoylation. The stimulation of AR activity is dependent upon sumoylation. Also functions as a transcriptional coactivator in the TGF-beta signaling pathway by increasing the activity of the SMAD3/SMAD4 transcriptional complex. Involved in transcriptional activation of a subset of NOTCH1 target genes including MYC. Involved in thymocyte and T cell development. Involved in the regulation of postmitotic positioning of pyramidal neurons in the developing cerebral cortex.
基因功能參考文獻(xiàn)：
1. Ectopic expression of Zmiz1 induces cutaneous squamous cell malignancies in a mouse model of cancer. PMID: 23426136
2. we show that activated NOTCH1 and ZMIZ1 collaborate to induce T-ALL in mice. PMID: 23161489
3. Zimp10 is found in somatic cells, outside the testis cords and ceases to be expressed in the adult testis. PMID: 19931425
4. A physiological role for Zimp10 in regulating Smad3/4-mediated transcription is demonstrated in mouse embryonic fibroblasts. PMID: 16777850
5. provides evidence to demonstrate a crucial role for Zimp10 in vasculogenesis PMID: 17967885
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亞細(xì)胞定位：

Nucleus, nucleoplasm. Cytoplasm.
組織特異性：

Expressed in brain.
數(shù)據(jù)庫(kù)鏈接：

KEGG: mmu:328365

STRING: 10090.ENSMUSP00000124863

UniGene: Mm.227484