Recombinant Mouse Xaa-Pro dipeptidase (Pepd)

中文名稱：

小鼠Pepd重組蛋白
貨號(hào)：

CSB-YP604737MO
規(guī)格：
來源：

Yeast
其他：

中文名稱：

小鼠Pepd重組蛋白
貨號(hào)：

CSB-EP604737MO
規(guī)格：
來源：

E.coli
其他：

中文名稱：

小鼠Pepd重組蛋白
貨號(hào)：

CSB-EP604737MO-B
規(guī)格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

小鼠Pepd重組蛋白
貨號(hào)：

CSB-BP604737MO
規(guī)格：
來源：

Baculovirus
其他：

中文名稱：

小鼠Pepd重組蛋白
貨號(hào)：

CSB-MP604737MO
規(guī)格：
來源：

Mammalian cell
其他：

產(chǎn)品詳情
產(chǎn)品評(píng)價(jià)
靶點(diǎn)詳情

產(chǎn)品詳情

純度：

>85% (SDS-PAGE)
基因名：

Pepd
Uniprot No.：

Q11136
別名：

Pepd; Pep4Xaa-Pro dipeptidase; X-Pro dipeptidase; EC 3.4.13.9; Imidodipeptidase; Peptidase 4; Peptidase D; Proline dipeptidase; Prolidase
種屬：

Mus musculus (Mouse)
蛋白長(zhǎng)度：

Full Length of Mature Protein
表達(dá)區(qū)域：

2-493
氨基酸序列

ASTVRPSFS LGNETLKVPL ALFALNRQRL CERLRKNGAV QAASAVVLQG GEEMQRYCTD TSIIFRQESF FHWAFGVVES GCYGVIDVDT GKSTLFVPRL PDSYATWMGK IHSKEYFKEK YAVDDVQYTD EIASVLTSRN PSVLLTLRGV NTDSGSVCRE ASFEGISKFN VNNTILHPEI VECRVFKTDM ELEVLRYTNR ISSEAHREVM KAVKVGMKEY EMESLFQHYC YSRGGMRHTS YTCICCSGEN AAVLHYGHAG APNDRTIKDG DICLFDMGGE YYCFASDITC SFPANGKFTE DQKAIYEAVL RSCRTVMSTM KPGVWWPDMH RLADRIHLEE LARIGLLSGS VDAMLQVHLG AVFMPHGLGH FLGLDVHDVG GYPEGVERID EPGLRSLRTA RHLEPGMVLT VEPGIYFIDH LLDQALADPA QACFFNQEVL QRFRNFGGVR IEEDVVVTDS GMELLTCVPR TVEEIEACMA GCDKASVPFS GQK
蛋白標(biāo)簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產(chǎn)品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復(fù)溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲(chǔ)存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質(zhì)期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項(xiàng)：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

功能：

Splits dipeptides with a prolyl or hydroxyprolyl residue in the C-terminal position. Plays an important role in collagen metabolism because of the high level of iminoacids in collagen.
基因功能參考文獻(xiàn)：
1. The findings identify peptidase D, an ubiquitously expressed intracellular peptidase, as a potential novel marker of colitis. PMID: 28323866
2. PEPD is a ligand of EGFR and presents a novel mechanism of EGFR activation PMID: 23212918
3. The dark-like mutation causes cardiomyocyte hypertrophy due to loss-of-function of peptidase d (Pepd). PMID: 21472842
4. NO stimulates prolidase activity by increasing serine/threonine phosphorylation through PKG-cGMP pathway PMID: 16167338
蛋白家族：

Peptidase M24B family, Eukaryotic-type prolidase subfamily
數(shù)據(jù)庫鏈接：

KEGG: mmu:18624

STRING: 10090.ENSMUSP00000075683

UniGene: Mm.69751