Recombinant Mouse Transcriptional enhancer factor TEF-5 (Tead3)

中文名稱：

小鼠Tead3重組蛋白
貨號：

CSB-YP023365MO
規(guī)格：
來源：

Yeast
其他：

中文名稱：

小鼠Tead3重組蛋白
貨號：

CSB-EP023365MO
規(guī)格：
來源：

E.coli
其他：

中文名稱：

小鼠Tead3重組蛋白
貨號：

CSB-EP023365MO-B
規(guī)格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

小鼠Tead3重組蛋白
貨號：

CSB-BP023365MO
規(guī)格：
來源：

Baculovirus
其他：

中文名稱：

小鼠Tead3重組蛋白
貨號：

CSB-MP023365MO
規(guī)格：
來源：

Mammalian cell
其他：

產(chǎn)品詳情
產(chǎn)品評價
靶點詳情

產(chǎn)品詳情

純度：

>85% (SDS-PAGE)
基因名：

Tead3
Uniprot No.：

P70210
別名：

Tead3; Tcf13r2; Tef5; Transcriptional enhancer factor TEF-5; DTEF-1; ETF-related factor 1; ETFR-1; TEA domain family member 3; TEAD-3
種屬：

Mus musculus (Mouse)
蛋白長度：

Full Length of Mature Protein
表達區(qū)域：

2-439
氨基酸序列

ASNSWTANSSPGEAREDGSEGLDKGLDNDAEGVWSPDIEQSFQEALAIYPPCGRRKIILS DEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARKKVREYQVGIKAMNLDQVSKDK ALQSMASMSSAQIVSASVLQNKFSPPSPLPQAVFSSSSRFWSSPPLLGQQPGPSQDIKPF AQPAYPIQPPLPPALNSYESLAPLPPAAASATASAPAWQDRTIASSRLRLLEYSAFMEVQ RDPDTYSKHLFVHIGQTNPAFSDPPLEAVDVRQIYDKFPEKKGGLKELYEKGPPNAFFLV KFWADLNSTIQEGPGAFYGVSSQYSSADSMTISVSTKVCSFGKQVVEKVETEYARLENGR FVYRIHRSPMCEYMINFIHKLKHLPEKYMMNSVLENFTILQVVTSRDSQETLLVIAFVFE VSTSEHGAQHHVYKLVKD
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產(chǎn)品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復(fù)溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質(zhì)期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產(chǎn)品評價

靶點詳情

功能：

Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein MST1/MST2, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Acts by mediating gene expression of YAP1 and WWTR1/TAZ, thereby regulating cell proliferation, migration and epithelial mesenchymal transition (EMT) induction.
基因功能參考文獻：
1. Experimental evidence for non-AUG translation initiation of human TEF-5. This non-AUG start site, AUA, is conserved in mouse. PMID: 10379887
2. DTEF-1 is a target for alpha(1)-adrenergic activation of the skeletal muscle alpha-actin gene in cardiac myocytes PMID: 11986313
亞細胞定位：

Nucleus.
組織特異性：

Expressed in embryos as well as in many adult tissues.
數(shù)據(jù)庫鏈接：

KEGG: mmu:21678

STRING: 10090.ENSMUSP00000110447

UniGene: Mm.6655